MicroRNAs (miRNAs) are small preserved non-coding RNA molecules that regulate gene expression post-transcriptionally by targeting the 3' UTR of mRNAs for translational repression or degradation. The rising evidence has established the significant role of miRNAs within the regulation of immune system and the prevention of autoimmunity. MiR-146a has obtained an importance as a modulator of differ...

Quantitative researching on the degree of incidence between the logistics industry and relevant macroscopic system elements is the basis of reasonable and scientific policy on industrial development. In the light of the macro-level, the logistics industry system is consisted of multiple macroscopic agents such as macro-economic, infrastructure, social environment, market demanding, the traditio...

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Purpose: Integrated health and social care is necessarily complex since the competence needed for carrying out the task of care does not lie within one individual provider organization, but requires deliberate co-operation between different providers. In this world, the primary managerial task is variously seen as seeking the efficient administration of human and material resources, and achievi...

In this study, a new adaptive controller is proposed for position control of pneumatic systems. Difficulties associated with the mathematical model of the system in addition to the instability caused by Pulse Width Modulation (PWM) in the learning-based controllers using gradient descent, motivate the development of a new approach for PWM pneumatics. In this study, two modified Feedback Error L...

In this paper, a novel adaptive sliding mode control for rigid robot manipulators is proposed. In the proposed system, since there may exist explicit unknown parameters and perturbations, a Lyapunov based approach is presented to increase system robustness, even in presence of arbitrarily large (but not infinite) discontinuous perturbations. To control and track the robot, a continuous controll...

In this paper, we introduce a new hyperchaotic complex T-system. This system has complex nonlinear behavior which we study its dynamical properties including invariance, equilibria and their stability, Lyapunov exponents, bifurcation, chaotic behavior and chaotic attractors as well as necessary conditions for this system to generate chaos. We discuss the synchronization with certain and uncerta...

Supporting the early phases of design requires, among others, support for the specification and use of multiple and evolving representations, and for the exchange of information between these representations. We consider a complex adaptive system as a model for the development of design representations, and present a semi-constructive algebraic formalism for design representations, termed sorts...