Substance dependence is characterized by compulsive substance seeking and high vulnerability to relapse. A major challenge in current substance addiction research is not only to understand the immediate effects of substances of abuse on brain operations. It is also to define, at the behavioral and neural levels, how cognitive, emotional, and motivational processes interact with substance use in...

Development of new treatments for drug addiction will depend on high-throughput screening in animal models. However, an addiction biomarker fit for rapid testing, and useful in both humans and animals, is not currently available. Economic models are promising candidates. They offer a structured quantitative approach to modeling behavior that is mathematically identical across species, and accru...

In 2001, the American Society of Addiction Medicine Patient Placement Criteria, Second Edition, Revised (ASAM PPC-2R) (American Society of Addiction Medicine, 2001) introduced the concepts of dual diagnosis capability (DDC) and dual diagnosis enhanced (DDE) addiction programs into the national lexicon. The original definitions of DDC and DDE addiction programs were relatively brief. DDC program...

This article reviews the treatment history of 100 hospital-treated heroin addicts and 100 hospital-treated alcohol-dependent individuals. The two cohorts were prospectively followed for 20 and 12 years respectively and factors related to relapse and freedom from relapse were sought. Premorbid social stability, especially stable employment history, proved a more effective predictor of long-term ...

BACKGROUND The aim of this study was to determine which predictors influence the risk of relapse among a cohort of amphetamine-type substance (ATS) users in Iran. METHODS A Cox proportional hazards model was conducted to determine factors associated with the relapse time in the Matrix treatment program provided by the Iranian National Center of Addiction Studies (INCAS) between March 2010 and...

conclusions it is suggested that for addiction rehabilitation and relapse prevention, health practitioners should not only provide an intervention program to their patients, but they should design a program for families to participate in the treatment as well so that patients can function at a higher level of wellness. therefore, the family participation program should be reinforced as part of ...

introduction: drug addiction could lead to severe impairments in executive and neurocognitive functions but study on the impact of hydrochloride heroin on executive functions has remained in infancy in iran. the aim of this study was to examine the relationship between addiction to hydrochloride heroin and executive functioning in several cognitive domains including mental flexibility, abstract...

This essay will reexamine research on the relationship between human memory and addiction. paper review several studies that discussed how systems in brain are involved acquisition of behavior is learned associated with development drug addiction relapse. Additional information reveals when individuals make transition from recreational or impulsive use to compulsive abuse, which may result a ne...