Over a third of the US population is obese and at high risk for developing type 2 diabetes, insulin resistance, and other metabolic disorders. Obesity is considered a chronic low-grade inflammatory condition that is primarily attributed to expansion and inflammation of adipose tissues. Indeed, adipocytes produce and secrete numerous proinflammatory and anti-inflammatory cytokines known as adipo...

OBJECTIVES To study the associations of adipokines with recovery from upper extremity soft tissue disorders (UESTDs) and to explore whether overweight or obesity modify these associations. METHODS In this follow-up study, patients seeking medical advice due to incipient upper extremity symptoms with symptom duration <1 month were included (n = 163). The outcome of the study was full or substa...

Background and Objective. The role of adipokines in regulation of immune responses has been recognized, but very little is known about their impact on multiple sclerosis (MS). In this study, we analysed whether the major adipokines are differentially expressed in plasma of patients with different MS subtypes and clinically isolated syndrome (CIS) and explored their association with major diseas...

Rationale: Inverse association between serum levels of vitamin D and obesity has been pointed out in several studies. Our aim was to identify the associations a large panel anthropometric markers adipokines, by sex, population-based cohort apparently healthy subjects.

Liver fibrosis involves different cell types, and should be regarded as a "wound healing" response that occurres in conditions of chronic liver injury and is characterized by inflammation, activation of matrix-producing cells, matrix deposition and remodeling, and epithelial cell regeneration or an attempt thereof. Liver damage may be caused by several agents or conditions, resulting in differe...