INTRODUCTION Adrenal myelolipoma is a rare, benign neoplasm that is usually asymptomatic, unilateral and nonsecreting. It develops within the adrenal gland and is composed of mature adipose tissue with elements of the hematopoietic series. We describe the case of what is, to the best of our knowledge, one of the largest secreting adrenal myelolipomas reported in the literature. CASE PRESENTAT...

Adrenocortical tumour have been described in patients with 21-hydroxylase deficiency. These tumours are usually considered to be ACTH – dependent, as diffuse adrenal cortical hyperplasia is commonly seen. We report adrenal cortical tissue tumours developed in three patients with untreated congenital adrenal hyperplasia due to 21-hydroxylase deficiency. All of them had symptoms of adrenogenital ...

The unusual case is described of a benign parotid gland neoplasm with intermingled sebaceous and lymphoid tissue, synchronous to breast cancer. In the past, the patient had undergone a simple surgical procedure for a cystic parotid gland lesion in that same gland. Secondary neoplasms have only occasionally been reported, since there are few cases for corroborating the strong correlation between...

The role of inflammation has been shown in the pathogenesis of epilepsy, while glucocorticoids and adrenaline have anti-inflammatory effects. The aim of the present study was to investigate the effects of adrenaline, prednisolone, and indomethacin on caffeine-induced epilepsy (epileptiform activity) in rats and to examine the mechanism of the pro-epileptic effect of indomethacin. The adrenalect...

Adrenal myelolipoma is a rare benign neoplasm of mesenchymal origin composed mature fatty tissue and bone marrow elements. It non-functioning tumor, usually asymptomatic commonly detected incidentally during evaluation for unrelated symptoms; hence, it referred to as an “incidentaloma”. Large myelolipomas can cause mass effects vague abdominal pain, spontaneous tumor rupture with massive hemorr...

TRH is a hypophysiotropic peptide that acts mainly via the hypothalamic-pituitary-thyroid axis, but TRH immunoreactivity is also detected in several peripheral tissues. PCR with two pairs of primers enabling amplification of three fragments of TRH complementary DNA (cDNA) was used to demonstrate local production of TRH. Products of the expected size were detected in the testis, adrenal gland, l...

OBJECTIVE To evaluate predictors of survival time in dogs undergoing adrenalectomy and identify risk factors associated with adrenal gland tumor metastasis and vein thrombosis. DESIGN Retrospective case series. ANIMALS 52 dogs with primary adrenal gland tumors. PROCEDURES Medical records were reviewed. Signalment, tumor features, and information from surgical procedures were evaluated to ...

The distribution pattern of nerves immunoreactive to neuronal factors typical for sensory neurons, such as substance P (SP), calcitonin gene – related peptide (CGRP), somatostatin (SOM), galanin (GAL) and nitric oxide synthase (NOS), used here as the marker of nitrergic neurons was studied by single immunofluorescence technique in various parts of the porcine adrenal gland i.e. subcapsular regi...

Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm, usually occurring in the pleura. Pararenal SFT, mimicking an adrenal gland or renal tumor, as here described, is extremely rare. We report a case of a right suprarenal SFT, incidentally discovered by abdominal ultrasound in a 54-year-old woman carrying a point neurofibromatosis 1 (NF1) gene mutation. Preoperative diagnostic work-up w...