The number of pregnant women of advanced maternal age has increased worldwide. Women in this group have an increased chance of fetal abnormality. To explore Japanese women's experiences regarding maternal age-specific risks and prenatal testing, we conducted a descriptive qualitative study. Semi-structured interviews were conducted with 16 women aged 35 years or over who had given birth within ...

Aneuploidy is a leading genetic cause of birth defects and lower implantation rates in humans. Most errors in chromosome number originate from oocytes. Aneuploidy in oocytes increases with advanced maternal age. Recent studies support the hypothesis that cohesion deterioration with advanced maternal age represents a leading cause of age-related aneuploidy. Cohesin generates cohesion, and is est...

Background: Extremes of maternal age adversely affect pregnancy outcomes. Teenage pregnancy is a public health problem and is known to be associated with adverse pregnancy outcomes. Advanced maternal age is a risk factor for pregnancy outcome. Saudi Arabia suffers the dual burden of teenage pregnancy and older pregnancy. Objectives: To explore the effects of maternal age on pregnancy and its ou...

BACKGROUND Advanced maternal age is associated with higher risks of intrapartum complications. However, the effect of maternal age on the risk of perinatal death due to these complications is unclear. The aim of the present study was to determine the association between maternal age and delivery-related perinatal death at term. METHODS In this retrospective cohort study, birth records of 1,04...