Genetically modified (GM) strains now exist for many organisms, producing significant promise for agricultural production. However, if these organisms have some fitness advantage, they may also pose an environmental harm when released. High mating success of GM males relative to WT males provides such an important fitness advantage. Here, we provide documentation that GM male medaka fish modifi...

it is well known that the matrix exponential function has practical applications in engineering and applied sciences. in this paper, we present some new explicit identities to the exponential functions of a special class of matrices that are known as central-symmetric $x$-form. for instance, $e^{mathbf{a}t}$, $t^{mathbf{a}}$ and $a^{mathbf{a}t}$ will be evaluated by the new formulas in this par...

This series of debates was initiated for the Journal of Applied Physiology because we believe an important means of searching for truth is through debate where contradictory viewpoints are put forward. This dialectic process whereby a thesis is advanced, then opposed by an antithesis, with a synthesis subsequently arrived at, is a powerful and often entertaining method for gaining knowledge and...

This series of debates was initiated for the Journal of Applied Physiology because we believe an important means of searching for truth is through debate where contradictory viewpoints are put forward. This dialectic process whereby a thesis is advanced, then opposed by an antithesis, with a synthesis subsequently arrived at, is a powerful and often entertaining method for gaining knowledge and...

A new boundary-integral formulation is proposed to analyze the heat transfer in zoned three-dimensional geometries. The proposed formulation couples the boundary formula, the gradient of the boundary formula, and the exterior formula. An advantage of this formulation over the traditional methods is that any linear condition at the interface between subdomains may be incorporated into the formul...

Alleles causing colour-blindness are present in humans at non-negligible levels, and it is not yet understood how colour-blindness is maintained, since colour-vision probably provides a selective advantage, e.g. when foraging. We show that after dark-adaptation colour-blinds had lower light perception thresholds than colour-normals (0.44 log-units), which may give a selective advantage under sc...

BACKGROUND In the first decade of this century players in the National Football League, the NFL community, fans, even the public at large, became aware that multiple concussions, heretofore considered inconsequential, could have devastating consequences later in life. RESULTS Since 1978, each one of the 32 teams in the NFL plays 16 games in the regular season. In the 25 years from 1978 to 200...