Adverse effects of /3-adrenergic receptor blocking drugs can be divided into two categories: 1) those that result from known pharmacological consequences of /3-adrenergic receptor blockade; and 2) other reactions that do not appear to result from /3-adrenergic receptor blockade. Adverse effects of the first type include bronchospasm, heart failure, prolonged hypoglycemia, bradycardia, heart blo...

Managing patients with multimorbidity often results in polypharmacy: the prescription of multiple drugs. However, the long-term effects of specific combinations of drugs and diseases are typically unknown. In particular, drugs prescribed for one condition may result in adverse effects for the other. To investigate which types of drugs may affect the further progression of multimorbidity, we que...

Combined use of an opioid with a psychostimulant is popular among drug abusers. Such “polydrug use” may increase drug effects or attenuate adverse effects of either drug alone. We proposed that a combination of methamphetamine (meth) and morphine may change physical opioid withdrawal symptoms. Adult male rats were chronically injected with cumulative subcutaneous (s.c.) doses of morphine, meth ...

Adverse effects of beta-adrenergic receptor blocking drugs can be divided into two categories: 1) those that result from known pharmacological consequences of beta-adrenergic receptor blockade; and 2) other reactions that do not appear to result from beta-adrenergic receptor blockade. Adverse effects of the first type include bronchospasm, heart failure, prolonged hypoglycemia, bradycardia, hea...

Many people have turned away from conventional medicines, with the belief that ‘natural’ substances like herbs are safer than synthetic substances. This belief is augmented by many other unwarranted claims such as herbal products do not contain chemicals while conventional medicines do, thus contributing to the latter’s side effects. The increasing use of herbal medicines has resulted in concer...

the aims of this study were to determine hippuric acid and toluene in urine samples, airborne toluene levels, health effects, and to describe any correlation between specimen samples. seventy-five printing workers exposed to toluene at work (exposed group), and 60 nonexposed people (control group) were studied. study participants were selected from same factories in the different positions. uri...

abstract background totally implantable central venous access devices (ports) have been available for over 10 years, but have not been achieved widespread use in pediatric oncology patients. ports facilitate the administration of chemotherapy in children with cancer. materials and methods in this study, early complications of implantable central venous access devices in children with different ...