Extracting adverse drug events receives much research attention in the biomedical community. Previous work adopts pipeline models, firstly recognizing drug/disease entity mentions and then identifying adverse drug events from drug/disease pairs. In this paper, we investigate joint models for simultaneously extracting drugs, diseases and adverse drug events. Compared with pipeline models, joint ...

BACKGROUND The Beers criteria identify inappropriate use of medications in older adults. The number of and risk for adverse events from these medications are unknown. OBJECTIVE To estimate the number of and risk for emergency department visits for adverse events involving Beers criteria medications compared with other medications. DESIGN Nationally representative, public health surveillance...

background: the reporting of adverse drug reactions (adrs) by nurses in hospitals is very important.aims: this study was aimed at investigating the impact of an educational intervention to improve adr reporting and whethertrained nurses had better knowledge, attitude, and practice toward adr reporting. materials and methods: a total of 300 nurses in a tertiary care teaching hospital in tehran, ...

background: s. alopecuroides, z. officinale and m. officinalis are used traditionally in the treatment of pain. objective: to evaluate the plants effects in the rat formalin test and their activity on the opioid receptors. methods: each rat was placed individually in a cage for 30 min to get acclimated. then 0.05 ml of 10% formalin was injected subcutaneously into the dorsal surface of the righ...

background and aims : adverse drug reactions (adrs) are one of the major leading causes of death in the world. this study was designed and conducted because of the importance of adverse events in the cancer treatment setting and regarding this issue there is no study exploring adverse reactions of acute hematologic malignancy chemotherapy in iranian population. methods : this was a prospective,...

hepatic toxicity is the most serious adverse effect of anti tuberculosis drugs. this study was performed to evaluate efficacy of silymarin as a hepatoprotective herbal agent. in a randomized double blind clinical trial 70 new cases of pulmonary tuberculosis were divided into two groups. the intervention group was assigned to receive silymarin and the control group received placebo. tuberculosis...

thrombolytic agents are among the medications that are used widely for the treatment of thromboembolic disorders and myocardial infarction (mi). despite the world-wide availability of newer specific agents, streptokinase (sk) is still the most frequently used medication from this class in iran. hence we conducted this study to review the adverse reactions to this medication which were reported ...

background: coronary computed tomography angiography (ccta) is a well-known method for evaluating anatomic coronary stenosis, but the reliability of ccta to predict cardiovascular events is an issue of controversy. materials and methods: in this prospective observational study, 58 patients with acute chest pain and low-to-moderate risk were selected and ccta was performed on them. during follow...