نتایج جستجو برای: afb
تعداد نتایج: 1659 فیلتر نتایج به سال:
Aflatoxin B(1) (AFB(1)), a mycotoxin produced by Aspergillus flavus, is oxidized by cytochrome P450 enzymes to aflatoxin B(1)-8,9-epoxide, which alkylates DNA at N7-dG. Under basic conditions, this N7-dG adduct rearranges to yield the trans-8,9-dihydro-8-(2,6-diamino-4-oxo-3,4-dihydropyrimid-5-yl-formamido)-9-hydroxy aflatoxin B(1) (AFB(1)−FAPY) adduct. The AFB(1)−FAPY adduct exhibits geometric...
BACKGROUND Lung cancer screening with low-dose CT (LDCT) scan has been demonstrated to reduce lung cancer mortality. Preliminary reports suggested that up to 20% of lung cancers may be CT scan occult but detectable by autofluorescence bronchoscopy (AFB). We evaluated the prevalence of CT scan occult, invasive, and high-grade preinvasive lesions in high-risk participants undergoing screening for...
OBJECTIVE To identify factors associated with negative direct sputum examination among African and Cambodian patients co-infected by Mycobacterium tuberculosis and HIV. DESIGN Prospective multicenter study (ANRS1260) conducted in Cambodia, Senegal and Central African Republic. METHODS Univariate and multivariate analyses (logistic regression) were used to identify clinical and radiological ...
BACKGROUND Tuberculosis (TB) causes 1.45 million deaths annually world wide, the majority of which occur in the developing world. Active TB disease represents immune failure to control latent infection from airborne spread. Acid-fast bacillus (AFB) seen on sputum smear is a biomarker for contagiousness. METHODS We enrolled 73 tuberculosis patients with extensive infiltrates into a research st...
To the Editor—I read with interest the case report on oesophageal tuberculosis mimicking carcinoma published in the December issue of the Hong Kong Medical Journal.1 We encountered a similar case where the ulcer was located in the proximal half of the oesophagus and had an elevated ulcerated edge. Our patient also had abnormalities in the stomach and the duodenum, an external compression of the...
BACKGROUND Bronchial intraepithelial lesions may be precursors of central airway lung carcinomas. Identification and early treatment of these preinvasive lesions might prevent progression to invasive carcinoma. METHODS We systematically reviewed the literature to develop evidence-based recommendations regarding the diagnosis and treatment of intraepithelial lesions. RESULTS The risk and tim...
Nerve biopsy examination is an important auxiliary procedure for diagnosing pure neural leprosy (PNL). When acid-fast bacilli (AFB) are not detected in the nerve sample, the value of other nonspecific histological alterations should be considered along with pertinent clinical, electroneuromyographical and laboratory data (the detection of Mycobacterium leprae DNA with polymerase chain reaction ...
we carried out prospective study on 121 cases of cervical tuberculous lymphadenitis during a 5-years period (1990-1995) in order to determine the correlation between clinical, histological and microbiological finding in establishing the tuberculous lymphadenitis diagnosis. biopsy was done in 96 cases, of which 93 specimens (96%) were compatible with tuberculous lymphadenitis, with 17 cases posi...
Aqueous-phase reforming (APR) of model compounds bio-oil aqueous fraction (AFB) was studied at different operating conditions. Substrate conversion, carbon-to-gas yield (CCgas) and hydrogen alkanes production were evaluated. Levoglucosan, hydroxyacetone, furfural acetic acid selected as representative AFB tested in batch APR concentrations (1–5 %wt.), temperatures (175–220 °C) reaction times (0...
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