The linker histone H1 has a fundamental role in DNA compaction. Although models for H1 binding generally involve the H1 C-terminal tail and sites S1 and S2 within the H1 globular domain, there is debate about the importance of these binding regions and almost nothing is known about how they work together. Using a novel fluorescence recovery after photobleaching (FRAP) procedure, we have measure...

Haemangioma of the cervix is an extremely rare benign lesion, and only a few sporadic cases have been reported to date. In the present report we describe a case of Haemangioma of the cervix that was diagnosed in a 28-year-old patient who consulted for post coital bleeding.

The paper presents personal experiences from the development and application of automation solutions, mainly in industrial environments, on six different decades spanning from late 1960’s to early 2010’s and relates them to their historical context. During the covered period tremendous developments occurred in both methodologies and enabling technologies. During and after the Second World War, ...

BACKGROUND Caesarean section (CS) rates are increasing worldwide and the most common reason is repeat CS following previous CS. For most women a vaginal birth after a previous CS (VBAC) is a safe option. However, the rate of VBAC differs in an international perspective. Obtaining deeper knowledge of clinicians' views on VBAC can help in understanding the factors of importance for increasing VBA...

BACKGROUND Meta-analyses of studies investigating the impact of maternal environmental tobacco smoke (ETS) on birth weight have not produced robust findings. Although, ante natal ETS exposure probably reduces infant's birth weights, the scale of this exposure remains unknown. We conducted a large, cohort study to assess the impact of ETS exposure on birth weight whilst adjusting for the many fa...

Human cervicovaginal mucus (CVM) is a viscoelastic gel containing a complex mixture of mucins, shed epithelial cells, microbes and macromolecules, such as antibodies, that together serve as the first line of defense against invading pathogens. Here, to investigate the affinity between IgG and different mucus constituents, we used Fluorescence Recovery After Photobleaching (FRAP) to measure the ...

A series of N-ethyl phthalimide esters 4(a-n) were synthesized and characterized by spectroscopic studies. Further, the molecular structure of majority of compounds were analysed by single crystal X-ray diffraction studies. The X-ray analysis revealed the importance of substituents on the crystal stability and molecular packing. All the synthesized compounds were tested for in vitro antioxidant...

World War I is often said to have benefited British women by giving them the vote and by enabling them to take on traditionally male roles, including ones in science, engineering and medicine. In reality, conventional hierarchies were rapidly re-established after the Armistice. Concentrating mainly on a small group of well-qualified scientific and medical women, marginalized at the time and als...

This paper raises a number of issues in thinking about and addressing the intergenerational transmission of disadvantage. Starting with choice subject to constraints by parents as determining outcomes for children, the paper identifies sequences of interventions to relieve “binding constraints” in the expansion of education. But the fact that parents choose for children is shown to raise a numb...

BACKGROUND The objective was to determine how postmenopausal bleeding (PMB) is managed in Sweden today, and to relate the findings to a new evidence-based algorithm for the management of PMB. METHODS A questionnaire regarding the role of ultrasound and the use of different endometrial biopsy methods in the management of PMB was sent to all 61 gynecologic departments in Sweden. RESULTS Fifty...