Amino acid enantiomeric (D/L) ratios in the mollusk Mercenaria are compared with recently published biostratigraphic and/or U-series solitary coral data from 22 Quaternary localities on the central and southern Atlantic Coastal Plain. In all cases, local relative aminostratigraphic sequences are consistent with relative ages inferred from U-series or biostratigraphic data, although occasionally...

The objective of this study was to assess the influence of age on the efficacy and toxicity of methotrexate in rheumatoid arthritis. Four hundred and sixty-nine patients were separated according to the age of onset of methotrexate treatment; before 65 yr (group 1, n = 416) and after 65 yr (group 2, n = 53). No difference was found in the evolution of clinical and biological parameters between t...

Ninety-eight patients with differentiated thyroid carcinoma were studied. Actuarial methods were used to investigate the 10-yr probability of survival (pS) and disease-free survival (pDFS). Our results show that the pDFS is a function of: (1) clinicopathologic stage: Stages I-II, pDFS = 90.9% +/- 5.0% versus Stages III-IV, pDFS = 55.9% +/- 17.8% (p less than 0.005); (2) age: Age less than 45 yr...

OBJECTIVES Renal cell carcinoma (RCC) is uncommon in young adults. Based on the few studies published to date, it is difficult to determine whether this tumour has a particular progression pattern. This retrospective, multicentre study analysed RCC in young patients, defined as </=40 yr old, compared to RCC in older patients. METHODS Between 1988 and 2000, 1233 patients, 93 under 40 yr old an...

PURPOSE This study aimed to examine the prospective associations of physical activity at 11, 15, and 18 yr of age with cognitive performance in young adulthood in a large birth cohort study from Brazil. METHODS Participants were part of a large birth cohort study in Pelotas, Brazil (n = 3235 participants). Physical activity was self-reported at 11, 15, and 18 yr and was also objectively measu...

BACKGROUND The authors designed a prospective longitudinal study to investigate the hypothesis that advancing age is a risk factor for postoperative cognitive dysfunction (POCD) after major noncardiac surgery and the impact of POCD on mortality in the first year after surgery. METHODS One thousand sixty-four patients aged 18 yr or older completed neuropsychological tests before surgery, at ho...

Children with eczema and sensitization to foods are recommended skin care and, if food allergy is proven by challenge, an elimination diet. For most children the diet period is transient, but the process behind tolerance development and the influence of decreased allergen exposure is not fully known. The aim of the study was to investigate the effect of elimination diet on serum and salivary an...

Highly seasonal rainfall creates a pulse of litterfall in the southern Yucatan peninsula region, with cascading effects on the timing of essential nutrient fluxes, microbial dynamics, and vegetation growth. I investigated whether forest age or a regional environmental gradient related to rainfall has a greater effect on patterns of litterfall in this increasingly human-dominated landscape. Litt...

Our aim was to determine if women who regularly perform endurance exercise demonstrate age-related elevations in body mass and adiposity. Ninety-five healthy females were studied: premenopausal ( n = 28; mean ± SE age 30 ± 1 yr) and postmenopausal ( n = 31; 56 ± 1 yr) endurance-trained runners and premenopausal ( n = 17; 29 ± 1 yr) and postmenopausal ( n = 19; 61 ± 1 yr) sedentary controls. In ...

Radiocarbon dating was performed for the extracted organic fractions (cellulose-rich and humic acid fractions of plant fragment; fulvic acid, humic acid and humin fractions of humus substance) and shell from core sediments of the Erhai Lake, SW China. The 14C dating results reveal that there are considerable differences, but there apparently is a humic acid ≤ humin < fulvic acid fraction sequen...