objective: antioxidants are essential for sperm motility. calligonum extract possesses the important antioxidants catechin and quercetin. this study investigates the effects of calligonum extract on sperm parameters and the rate of apoptosis in testes of aging male mice. methods: we initially performed a dose response test with using three doses of calligonum (10 mg/kg, 30 mg/kg and 50 mg/kg). ...

background the use of long-term care services has risen and this trend is expected to continue as the population reaches old age. objectives this study was performed to assess the caring conditions in nursing homes. patients and methods this study was conducted with a qualitative approach using conventional qualitative content analysis. the study was conducted on 23 iranian participants includi...

vitamin d deficiency is the most under-diagnosed medical condition in postmenopausal women. there are few epidemiologic studies on vitamin d status of postmenopausal women in iran. this study aimed to investigate the 25-hydroxyvitamin d levels in postmenopausal women living in tehran, capital of iran. in this cross sectional study, 110 women were selected via convenience sampling method from me...

the immune system of mammalian organisms undergoes alterations that may account for an increased susceptibility to certain infections, autoimmune diseases, or malignancies. well characterized are age related defect in t cell functions and cell mediated immunity. although it is well established that the functional properties of t cells decrease with age, its biochemical and molecular nature is p...

age related skin disorders due to structural and functional changes in the skin of the elderly may increase health care costs. as a result of an increase in the number of aging population in iran, provision of dermatology services to the elderly group due to the limitation of resources and the high cost of those services will be a challenge for the health care system. moreover, by increasing th...

conclusions regular aerobic exercise could increase plasma klotho levels, and this could be an explanation for exercise-related anti-aging effects. background klotho is an anti-aging protein that is predominantly secreted by the kidneys. objectives the aim of the study was to measure and compare the circulating klotho levels in the serum of trained athletes and in healthy, non-athlete controls....

Interventions that target fundamental aging processes have the potential to transform human health and health care. A variety of candidate drugs have emerged from basic and translational research that may target aging processes. Some of these drugs are already in clinical use for other purposes, such as metformin and rapamycin. However, designing clinical trials to test interventions that targe...

It is well known that certain cognitive abilities decline with age. The ability to form certain new declarative memories, particularly memories for facts and events, has been widely shown to decline with advancing age. In contrast, the effects of aging on the ability to form new procedural memories such as skills are less well known, though it appears that older adults are able to acquire some ...