Aurora kinases (AKs) are serine/threonine kinases that are essential for cell division. Humans have three AK genes: AKA, AKB, and AKC. AKA is required for centrosome assembly, centrosome separation, and bipolar spindle assembly, and its mutation leads to abnormal spindle morphology. AKB is required for the spindle checkpoint and proper cytokinesis, and mutations cause chromosome misalignment an...

BACKGROUND To assess the level of parasite burden in a village community and the predisposing factors. METHODS Two hundred subjects each were recruited from three communities- Tyogbenda, Jato-Aka and Adikpo during an episode of free medical outreach. A simple random sampling method was adopted and a questionnaire was interviewer administered on relevant aspects of basic hygiene such as- sourc...

The integration of communication protocols into transport systems is a much adored research area today. Much of seminal work has been reported on the topic of intelligent transportation systems (ITS) in the recent years. Many advanced techniques have been garnered to improve online communication and to promote the security, comfort, and efficiency of ITS. Of primary importance to the effective ...

Granulomatosis with polyangiitis (GPA, formerly known as Wegener's Granulomatosis) is an autoimmune small vessel vasculitis which is highly associated with anti-neutrophil cytoplasmic antibodies (ANCA). The hallmarks of this condition are systemic necrotising vasculitis, necrotising granulomatous inflammation, and necrotising glomerulonephritis. The aetiology of granulomatosis with polyangiitis...

Four new sulfated sesquiterpene hydroquinones siphonodictyals E1-E4 (1-4) and cyclosiphonodictyol A (5) were isolated from a sample of the Caribbean sponge Aka coralliphagum collected off the coast of San Salvador in the Bahamas. The structures of the new compounds were elucidated on the basis of mass spectrometric and NMR spectroscopic analysis. Compounds 1-4 are derivatives of siphonodictyal ...

W ith government funding for bio-medical research stagnant or declining, scientists rely more than ever on industry support. Yet although that support is indispensible, it poses delicate challenges: Scientists and doctors are sometimes tempted to decide what's best for a sponsoring company rather than for patients. These conflicts of interest have sparked growing calls for transparency into ind...

Genetically engineered organisms (what many call GMOs – genetically modified organisms) are increasingly showing up in newspaper headlines, web sites, blogs, and email. There have been media splashes about new genetically engineered (GE) crop types, proposed labeling legislation, and even shocking photos claiming to show animals harmed by consuming GE crop products. After noting why it may be t...

Universal mobile telecommunication system (UMTS) has specified security mechanisms with extra features compared to the security mechanisms of previous mobile communication systems (GSM, DECT). A hardware implementation of the UMTS security mechanism is presented in this paper. The proposed VLSI system supports the Authentication and Key Agreement procedure (AKA), the data confidentiality proced...

Even though CDMA2000 wireless networks are being widely deployed as a cellular digital standard around the world, it has some hidden vulnerabilities concerned with security issues. The existing CDMA systems use authentication mechanism by CAVE (Cellular Authentication and Voice Encryption) algorithm. This authentication method has several disadvantages. Only one way authentication is provided, ...

With this often quoted statement, Albert Kahn sought to differentiate his firm’s approach from that of his peers and competitors in the first half of the twentieth century. Coinciding with the rapid industrialization of the American economy during this period, Albert Kahn Associates (AKA) developed to be the premier industrial architects of this country, if not of the entire world. Kahn’s pract...