AIMS/INTRODUCTION The nature of the action of concomitant liraglutide to stabilize postprandial blood glucose level (PBG) in patients on intensive insulin therapy with unstable PBG remains unclear. The aim was to identify the nature of liraglutide's actions to stabilize PBGs. MATERIALS AND METHODS The study participants consisted of 20 diabetes patients showing unstable PBGs after dinner desp...

Intrusion detection system aims at analyzing the severity of network in terms of attack or normal one. Due to the advancement in computer field, there are numerous number of threat exploits attack over huge network. Attack rate increases gradually as detection rate increase. The main goal of using data mining within intrusion detection is to reduce the false alarm rate and to improve the detect...

The inactivation of beef liver porphobilinogen synthase by the alkylating agents iodoacetate and iodoacetamide has been investigated. The synthase can be inactivated by these reagents only if the enzyme has been activated initially by sulfhydryl reducing agents. Inactivation by both iodoacetate and iodoacetamide was the result of modification of cysteinyl residues. A plot of the incorporation o...

The morpheein model of allosteric regulation can be applied as a novel approach to the discovery of small molecule allosteric modulators of protein function. Morpheeins are homo-oligomeric proteins where, under physiological conditions, the oligomer can dissociate, the dissociated units can change conformation, and the altered conformational state can reassociate to a structurally and functiona...

The 14C labelled inactive protein obtained by sodium borohydride reduction of the enzyme, porphobilinogen synthase of Rhodopseudomonas spheroides, in the presence of [4-14C]5-aminolevulinic acid, gave on acid hydrolysis and subsequent electrophoresis or two-dimensional chromatography a major radioactive spot which was confirmed to be N-epsilon-[4-(-5aminovaleric acid)]lysine (ALA-lysine) by com...

Photonics, the technology of photons (by analogy to electronics, the technology of electrons) will be the driving force for the advancement of areas such as communications and computing, information technology and probably others such as sensing. Photonic band gap (PBG) materials may answer many of their demands. Trying to understand the physics involved is a challenge very eagerly taken on by ...