Lonchocarpus cyanescensis one of the medicinal plants used in treatment diabetes mellitus Western Nigeria. This study was aimed at evaluating acute toxicity aqueous and methanolic leaf extracts Lonchocarpuscyanescens normal albino rats. Phytochemical screening pulverized plant revealed presence tannins, flavonoids, saponins, cardiac glycosides, steroids reducing sugars. The both showed no morta...

This study was carried out to evaluate the effect of honey intake on bile secretion, bile electrolytes, bilirubin and cholesterol levels including plasma cholesterol in albino rats. 20 male albino rats (200-210 g) were used in the study. The rats were assigned randomly into 2 groups (control and honey-fed groups), each group containing 10 rats. The control was fed on normal rat feed and water w...

Aims: The present study aimed to evaluate anti-diabetic properties of AgNPs/chitosan/ascorbic acid nanocomposites (Ag-NCs) in streptozotocin-induced diabetic rats. Main methods: Eighteen male Wistar albino rats were divided into three main groups (6 rats/group); control, and Ag-NCs groups. Control group: after a single dose citrate buffer (0.1 mol/l, i.p), the orally received 1 ml distilled wat...

In order to evaluate the toxicity of Cassia sieberiana leaf extract in albino rats with the aim of establishing its safe application in experimental and field trials, the acute toxicity of the aqueous extract of the leaves was studied in albino rats. Four experimental groups of albino rats (A, B, C, D) were respectively given intraperitoneal doses of 400, 800, 1600 and 3200 mg/kg body weight of...

Background: Semecarpus anacardium plant derivatives has been used since antiquity, The fruit and nut extract of Semecarpus anacardium shows various activities like antiatherogenic, anti-inflammatory, antioxidant, antimicrobial, antireproductive, CNS stimulant, hypoglycemic, anticarcinogenic. The present study is an attempt to explore the anti-inflammatory activity of ethanolic extract of fruits...

Allium cepa (onion) and Allium sativa (garlic) are bulbous herbs used as food item, spice and medicine in different parts of the world. The effects of onion and garlic on the osmotic fragility of red blood cells in albino rats were assessed in vivo and in vitro. In the in vivo studies, five albino rats weighing between 150 - 200g composed each of three study groups. Group A were administered 15...

Pitirrunthos /rirudiutir.s is a common perennial in the Negev desert and although its dense tufts are green all the year, it only occasionally is grazed by goats or gazelles (D. Ashkenazy, personal communication). Five furocoumarins were detected in the shoots of this plant.’ Some furocoumarins present in different members of the Umbelliferae are known to induce photosensitization in various an...

Thyroid status is an important determinant of cardiovascular function. We studied the changes in the aorta of hypothyroid rat at the post-pubertal stage, in addition to the ameliorating role of folic acid. Fifty male albino rats were equally divided into five groups; the first and second groups were the control and folic acid groups, respectively while the third group was the hypothyroid group ...

AIM To investigate the effect of in utero exposure to hydroxyprogesterone (HP) on liver metabolism in adult male albino rats. METHODS Pregnant Wistar strain albino rats were exposed to supra-normal levels (10 mg/kg and 25 mg/kg) of HP on days 1, 7 and 14 of pregnancy. The male pups were maintained under controlled conditions and the rats were killed 90 days after birth. The liver tissue was i...