allergic rhinitis  (ar) is  an  inflammatory  disorder  of  the  nasal  mucosa  with  high morbidity and prevalence. natural killer (nk) cells might have a role in ar. we aimed to evaluate the changes of the markers and receptors on nk cells in ar patients compared to the non-atopic controls. flow  cytometric  analysis was  used  with  double  staining  of  the  peripheral  blood mononuclear ce...

background: asthma, allergic rhinitis and eczema as a common disorder in childhood, has many epidemiologic variations in different geographic areas. this study aimed at determining the prevalence of pediatric allergic disease in rural area of babol. methods: this analytical-cross sectional study was performed in 2012 by random sampling on 2 groups of children the first group aged 6-7 years (n=1...

how to cite this article: ghaffari j, abbaskhanian a, jalili m, yazdani charati y. iq score of children with persistent or perennial allergic rhinitis: comparison with healthy children. iran j child neurol. 2014 summer; 8(3): 44-48.   abstract objective prevalence of allergies is different around the world. allergic rhinitis is a common chronic disease in children. intelligence quotient (iq) is...

the prevalence of allergic diseases such as asthma and allergic rhinitis is high in general population and aeroallergens are the most common allergens that cause air way inflammation. the aim of this study was an evaluation of clinical and laboratory findings in allergic patients and identification of the most common aeroallergen in these patients. a cross–sectional retrospective study was cond...

Background & Aims: Allergic diseases have increased in the last decade worldwide and researchers have been trying to introduce new strategies and drugs to treat these types of diseases. Nicotine shows anti-inflammatory properties and the studies have revealed that it can reduce the inflammation and the allergic responses. The mammalian target of rapamycin (mTOR) is a multifunctional protein kin...

Interleukin-5 is produced by a number of cell types, and is responsible for the maturation and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective cytokine as a result of the restricted expression of the interleukin-5 receptor on eosinophils and basophils. Eosinophils are a prominent feature in the pulmonary inflammation that is associated with allergic airwa...

Airway hyper-reactivity is a characteristic feature of many inflammatory lung diseases and is defined as an exaggerated degree of airway narrowing. Chemokines and their receptors are involved in several pathological processes that are believed to contribute to airway hyper-responsiveness, including recruitment and activation of inflammatory cells, collagen deposition and airway wall remodeling....

The selective recruitment of eosinophils in tissue is a striking feature of allergic diseases. Recently, a family of chemoattractant molecules, namely chemokines, has been described which potently activates eosinophil function in vitro. We have developed a murine model of eosinophil recruitment to compare the relative potency and efficacy of chemokines in vivo. Of the chemokines tested, only eo...

although response to intranasal steroid therapy has been reported in pa¬tients with allergic rhinitis, efficacy of some nasal steroids is noteworthy. this study was undertaken to evaluate the efficacy of a two-week course of fluticasone (flixonase) nasal spray vs. beclomethasone (beconase) nasal spray in patients with symptoms of allergic rhinitis referred to our clinic. this study reviewed six...