Acute appendicitis is perhaps the most common surgically correctable cause ofacute abdominal pain and its diagnosis remains difficult in many instances. Some ofthe signs and symptoms can be subtle to both the clinician and the patient and may notbe present in all the instances. Arriving at the correct diagnosis and decreasing therate of negative appendicectomy is essential. However a delay in d...

Systems biology analysis of immune signaling in peripheral blood mononuclear cells (PBMC) of melanoma patients receiving ipilimumab; basis for clinical response biomarker identification Drew Hotson, Ryan Alvarado, Andrew Conroy, Santosh Putta, Ester Simeone, Assunta Esposito, Mariaelena Capone, Gabriele Madonna, Antonio M Grimaldi, David Rosen, Spencer Liang, Alessandra Cesano, Paolo A Ascierto...

Resumo O objetivo deste artigo é o de analisar a atuação da organização não governamental (ONG) mexicana Centro Direitos Humanos das Mulheres (CEDEHM) no caso Alvarado contra México, perante sistema interamericano, fim revelar importância intermediação político-legal para os debates teóricos sobre mobilização normas internacionais direitos humanos. argumento central que tipo estabelecida pelas ...

This study reports for the first time molecular detection of Anaplasma platys infection in 4 (13.3%) of 30 Malaysian dogs investigated. A low occurrence (3.3%) of Babesia gibsoni was also noted, being detected in one of the 30 dogs. Rickettsia, Bartonella, Orientia tsutsugamushi, and Ehrlichia DNA were not detected in the dog blood samples. The role of A. platys as an agent of canine anaplasmos...

Las elecciones del 2018 en Costa Rica dejaron ver una versión discursiva que parecía improbable. Durante la segunda ronda de las donde se disputaron presidencia el Partido Acción Ciudadana (PAC) liderado por Carlos Alvarado y partido Restauración Nacional (RN) con candidato Fabricio Alvarado, mostró dialéctica cual, un lado, indica tradición socialdemócrata, esperable –aunque cuestionada–, pero...

Reseña sobre Bruno, Paula Alexandra Pita y Marina Alvarado. Embajadoras culturales. Mujeres latinoamericanas vida diplomática, 1860-1960. Rosario: Prohistoria, 2021.

I recently reviewed the paper published in this journal by Hernández-Alvarado et al., titled "Increase in Suicide Rates by Hanging in the Population of Tabasco, Mexico between 2003 and 2012" [1], and I noticed that the epidemiological concept "prevalence" is not correctly used.[...].

Ariel Castro-Lara, Viviana Guajardo, Rosemarie Fritsch, Ruben Alvarado, Graciela Rojas Investigations Support Office, Clinical Hospital, Universidad de Chile, Santiago, Chile Clinical Hospital, Faculty of Medicine, Universidad de Chile, Santiago, Chile School of Public Health, Faculty of Medicine, Universidad de Chile, Santiago, Chile Psychiatry Department, Faculty of Medicine, Universidad de L...

The epidermal growth factor receptor (EGFR) regulates cell proliferation in many tissues. A new structure of the Drosophila EGFR presented by Alvarado et al. (2010) reveals an asymmetric dimer with the ligand bound to only one subunit. The structure provides a rationale for the receptor's negative cooperativity and necessitates a reconsideration of models for activation of human EGFR.

Objective
 Appendicitis is the most common cause of extrauterine acute abdomen during pregnancy. There are scoring systems, such as Alvarado, based on physical examination and laboratory values developed for diagnosis appendicitis in general population. However, when it comes to pregnant women, effectiveness methods used daily practice decreases considerably. In our study, we aimed share d...