Periodontal disease is one of the most prevalent chronic disorders worldwide. It is accompanied by inflammation of the gingiva and destruction of periodontal tissues, leading to alveolar bone loss. Here, we focused on the role of adipokines, which are locally expressed by periodontal tissues, in the regulation of catabolic gene expression leading to periodontal inflammation. The expression of t...

Several studies have shown that surgical detachment of marginal gingiva close to the cervical cementum of molar teeth in a rat mandible is a distinct stimulus for alveolar bone resorption. Recently, we found that P2X4, an ATP-receptor, is significantly up-regulated in marginal gingival cells soon after surgery. We hypothesized that local release of ATP signaling through P2X4 elicits activation ...

Dietary fish oil has been shown to inhibit bone resorption and, therefore, the aim of the present study was to test the hypothesis that fish oil alters lipopolysaccharide (LPS)-induced hydroxyapatite loss in rat alveolar bone. Rats were divided into four groups. The animals injected with saline or Escherichia coli-derived LPS into the maxillary alveolar mucosa on the buccoapical site of the mol...

Tooth loss, especially in the anterior region, generates a loss of local bone structure affecting aesthetics and function for patient viable tactic is use deproteinized bovine block graft. This reconstructive method allows possibility partial or total reconstruction maxilla mandible safe predictable way, where it seeks maintenance three-dimensional structure, viability neoformation favoring imp...

Periodontal diseases are multifactorial, caused by polymicrobial subgingival pathogens, including Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia. Chronic periodontal infection results in inflammation, destruction of connective tissues, periodontal ligament, and alveolar bone resorption, and ultimately tooth loss. Enoxacin and a bisphosphonate derivative of enoxacin (bis...

Regarding the blood studies, several in­ vestigators . have reported higher than normal values for total calcium, total cholesterol, uric acid, sugar and phos­ phatase (in gingival blood) in various percentages of their cases. Lower than normal values have been reported for vitamin C, erythrocyte count and carbon dioxide combining power. Other workers have failed to confirm the findings for cal...

background and aims. considering the importance and prevalence of cardiovascular disease and periodontal disease, the aim of this study was to compare the amount of periodontal destruction in patients with coronary heart disease (chd) and healthy controls, using panoramic radiography. materials and methods. fifty-four individuals (27 patients with chd and 27 patients without chd) participated i...

Since the beginning of the 20th century, the concept of osteoconduction in bony changes in the oral cavity showed a wide range of biomaterials and their osteoinductive potential that emerged gradually and has to a large extent improved the quality of the bone prior to the placement of an implant. Alveolar bone loss is a major concern after tooth extraction in patients and therefore atraumatic e...

Augmentation of deficient and atrophic alveolar ridges is an important aspect of dental implant therapy with the goal of providing a functional restoration in harmony with adjacent natural dentition. Bone splitting technique is considered a distinguished augmentation method for treatment of deficient alveolar ridges. According to this procedure, the compromised alveolar ridge is opened from the...