To date, there is little in the way of theorizing or empirical work on the imagined endpoint of political action aimed at social change – the type of “dream” those engaged in action are attempting to bring into fruition. We suggest that previous approaches have focused narrowly on one type of social change – amelioration of collective grievances. In contrast, we argue that social change is much...

Introduction The b-haemoglobinopathies are of the most prevalent inherited disorders worldwide. b-thalassaemia is a single gene disorder affecting the b-globin gene, thus resulting in a lack or depleted availability of b -globin for formation of haemoglobin. b-thalassaemia has become a target for gene therapy based treatments in hope of a cure, or significant phenotype amelioration. The techniq...

Tanners, welders and workers in various industries are exposed to acute and chronic toxicity of these heavy metals world wide. The present work is undertaken to evaluate the genotoxic effects of Ni and Cr at two different exposure intervals with a single dose and the amelioration of this toxicity using curcumin. Ni in form of nickel chloride (4.216 X 10M) and Cr as potassium dichromate (1.36 X ...

Multiple Sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS). MS is characterized by an immune response directed against myelin sheath. This immune response results in demyelination, which leads to the clinical symptoms of MS. It is accepted that MS is mediated by T helper 1/ T helper 17 immune responses. However, the role of B cells and antibodies (Abs) ar...

Many patients with Parkinson's Disease (PD) experience significant cognitive and mood impairment -even early in the course of the disease. These mental impairments are only partially responsive to levodopa treatment and are often as disabling as the motor impairment, particularly in mid and late stages of the disease. Investigators have recently begun a search for new agents that can effectivel...

Introduction The b-haemoglobinopathies are of the most prevalent inherited disorders worldwide. b-thalassaemia is a single gene disorder affecting the b-globin gene, thus resulting in a lack or depleted availability of b -globin for formation of haemoglobin. b-thalassaemia has become a target for gene therapy based treatments in hope of a cure, or significant phenotype amelioration. The techniq...

A laboratory-scale study was conducted to investigate the effect of rhamnolipids (RLs) supplement on amelioration saline-alkali soils. The RLs improved soil aggregates stability and promoted formation macro-aggregates which increased by up 10.84% 15.92% in alkaline saline soil, respectively. In addition, amendment led a pH reduction from initial 8.87 7.80–7.84 salt rejection 20.72% remarkably a...