The early, de-embryonated chick blastoderm, cultured in vitro, closely simulates a phased culture of erythroid cells. This fact permits the study of hemoglobin synthesis from colorless erythroblast precursor cells to fully hemoglobinated erythrocytes. When b-aminolevulinic acid is added to colorless blastoderms, thereby by-passing &aminolevulinic acid synthetase, copious amounts of porphyrins, ...

Free-radicals production is involved in the toxicity of cadmium. The aim of this study was to determine whether biochemical changes occurred in the liver and kidney of cadmium exposed pups during gestation and lactation, and additionally to investigate the potential beneficial role of the administration of certain antioxidants against cadmium exposure damage. Pregnant Wistar rats received the f...