نتایج جستجو برای: ammine complex

تعداد نتایج: 784001  

Journal: :Journal of cell science 1992
D F Liu M el-Alfy C P Leblond

Previous investigators have examined mitochondrial DNA (mtDNA) in the electron microscope (EM) after extraction from mitochondria and rotary shadowing. We have observed mtDNA in situ by the osmiumammine procedure for specific staining of DNA in the EM. The procedure was modified to improve the regularity of the staining and then applied to the rapidly dividing cells present in mouse duodenal cr...

Journal: :Cancer research 1994
M J McKeage L R Kelland F E Boxall M R Valenti M Jones P M Goddard J Gwynne K R Harrap

JM216 is a novel antitumor platinum(IV) complex displaying oral activity, dose-limiting myelosuppression, and a lack of nephro- and neurotoxicity in rodents. It has been selected for clinical evaluation. The schedule dependency of its antitumor action against a murine (ADJ/PC6 plasmacytoma) and a human tumor model (PXN109T/C ovarian carcinoma xenograft) was studied in vivo. Single dose (q21d), ...

2005
Swee Y. Sharp Paul M. Rogers Lloyd R. Kelland

The mechanisms by which cis-diamminedichloroplatinum(II) (cisplatin) is transported across the plasma membrane (Le., passive diffusion versus active transport) were investigated in the 4!M and CH1 human ovarian carcinoma cell lines and their acquired cisplatin-resistant variants 4!McisR6 and CH!cisR6, respectively. Intracellular cisplatin accumuhation was significantly reduced (4.0 ± 1.7-fold) ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علامه طباطبایی - دانشکده ادبیات و زبانهای خارجی 1387

the present study is an experimental case study which investigates the impacts, if any, of skopos on syntactic features of the target text. two test groups each consisting of 10 ma students translated a set of sentences selected from advertising texts in the operative and informative mode. the resulting target texts were then statistically analyzed in terms of the number of words, phrases, si...

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