alzheimer’s disease (ad) is a neurodegenerative disease that is the most common type of dementia.ad includes 60_80% of dementia and most people with ad have more than 65 years old.ad causes losing neuronal activity by abnormal proteins. plaques of beta-amyloid and tangles of “tau” protein can lead to ad. recently evidence has found that ad may come from outside of central nervous system (cns) a...

A linear time-varying aggregate traffic flowmodel can be used to develop traffic flowmanagement strategies using optimization algorithms. However, there are few methods available in the literature to translate these aggregate solutions into practical control actions involving individual aircraft. In this paper, a computationally efficient disaggregation algorithm is proposed by employing a seri...

Alzheimer's desease is the most common age-related neurodegenerative disorder, and cognitive problems such as defects in learning and memory are of its symptoms.  Among the factors involved in the pathogenesis of the disease are biochemical disorders in protein production, oxidative stress, decreased acetylcholine secretion and inflammation of the brain tissue. Extra-neuronal accumulation ...

Kinetics of optical tweezers (OT)-induced spontaneous aggregation and disaggregation of red blood cells (RBCs) were studied at the level of cell doublets to assess RBC interaction mechanics. Measurements were performed under in vitro conditions in plasma and fibrinogen and fibrinogen + albumin solutions. The RBC spontaneous aggregation kinetics was found to exhibit different behavior depending ...

We study the influence of an external electromagnetic field of 1.8 GHz in the formation or disaggregation of long rouleau of identical erythrocyte cells. In particular we calculate the variation of the transmembrane potential of an individual erythrocyte illuminated by the external field due to the presence of the neighboring erythrocytes in the rouleau, and compare the total electric energy of...

Field observations of weathering Comp B (RDX/TNT 60/40) residue were made on a live-fire training range over four years. The Comp B residue was formed by low-order detonations of 120-mm mortar projectiles. Physical changes were the disaggregation of initially solid chunks into masses of smaller diameter pieces and formation of red phototransformation products that washed off with rain or tidal ...

a 64-year-old woman, with amyloid related kidney failure (on renal dialysis) had a bone scan because of pain in the right upper femur. the 99m tc-mdp images revealed marked hepatic uptake. in addition, there was right proximal femoral concentration of radiotracer, which corresponded to a fracture site. as an added finding, the same femor demonstrated circumferential uptake at the lower pole. th...

the study was undertaken to answer the question that how many patients with pigmentation of back and arms actually have amyloid deposits in pathology. 44 patients presenting with diffuse pigmentation of back and arms (dpoba) were selected. skin biopsies were performed in all cases from the affected sites. on all formalin fixed and paraffin embedded specimens, the following histochemical stains ...

A 64-year-old woman, with amyloid related kidney failure (On renal dialysis) had a bone scan because of pain in the right upper femur. The 99m Tc-MDP images revealed marked hepatic uptake. In addition, there was right proximal femoral concentration of radiotracer, which corresponded to a fracture site. As an added finding, the same femor demonstrated circumferential uptake at the lower po...