A 40-year-old patient with Type I Von Willebrand Disease presented for elective cesarean section. At the operating theater before delivery, while receiving cryoprecipitate, she developed an anaphylactic reaction requiring resuscitation. Once was hemodynamically stable, factor VIII/VWF concentrates were administered and operative delivery performed, a good maternal fetal outcome.

Modern views about the various causes of development anaphylactic shock in children and adolescents, classification based on pathophysiological mechanisms are observed survey. The algorithm diagnosis anaphylaxis shock, emergency assistance further management patients with as well issues its prevention presented.