OBJECTIVE To evaluate the associations between (1) antidrug antibody (ADAb) and therapeutic response, (2) ADAb and serum drug trough levels and (3) serum drug levels and therapeutic responses in rheumatoid arthritis (RA) patients receiving adalimumab or etanercept. Secondarily, we aim (1) to evaluate the concordance between radioimmunoassay and bridging ELISA for ADAb assessment and to evaluate...

This study evaluated the long-term (up to 4 years) efficacy and safety of entecavir ETV treatment and analysed the significance of baseline and on-treatment factors in long-term ETV outcomes in adolescents with chronic hepatitis B (CHB). We determined the cumulative virological and serological outcomes of 44 adolescents with CHB receiving ETV for up to 4 years. To investigate the dynamics of HB...

PURPOSE In this study, we aimed to report the results of a retrospective study carried out at our institute regarding cases of patients who had suffered proximal femoral fractures between January 2002 and February 2007, and who were treated with a proximal femoral nail. MATERIALS AND METHODS One hundred consecutive cases were included in the study. A case documentation form was used to obtain...

A 41-year-old female presented with a history of gradually increasing esotropia (ET) for 23 years. The best corrected visual acuity was 20/63 in both eyes. Refraction values were -18.50 (-1.00*55) in the right eye and -13.25 (-3.00*105) in the left eye. The axial length was measured as 29.35 mm for the right eye and 28.36 mm for the left eye. The patient's ocular motility was very restricted in...

OBJECTIVE Renal calculus disease is associated with recurrence after its surgical removal in large number of cases. Kulattha is acclaimed to have litholytic property in ayurvedic literature. We decided to compare the litholytic property of Kulattha with potassium citrate, an agent used to reduce stone recurrence in modern medicine. METHODS Forty seven patients with diagnosis of calcium oxalat...

background: photorefractive keratectomy is a popular mean to correct refractive errors of the eye and haze formation is one of the most important complications of the surgery. although standard dose of intraoperative mitomycin c has shown to be effective in reduction of this complication, potential side effects of mitomycin c promote us to show if the lower concentration of mitomycin c has t he...

J.G. Richardson (Ed.), Handbook of theory and research for the sociology of education. New York: Greenwood Press. Bousquet, M., & Willa, K. (Eds.). (2003). The politics of information: The electronic mediation of social change. Boulder, CO: Alt X Press. Brooks, F. (1995). The mythical man-month. Boston, MA: Addison-Wesley. (Original work published 1975) Hofstede, G. (1980). Culture’s consequenc...

Foetuses are a source of scientific information to understand the development and evolution of anatomical structures. The bony labyrinth, surrounding the organ of balance and hearing, is a phylogenetically and ecologically informative structure for which still little concerning growth and shape variability is known in many groups of vertebrates. Except in humans, it is poorly known in many othe...

This study was aimed to validate the 5th and 6th editions of tumor-node-metastasis (TNM) system for patients with hepatocellular carcinoma (HCC), and attempted to improve prognostic stratification by modifying the 6th edition according to vascular invasion and tumor size. From 1986 to 2002, a total of 5,613 HCC cases from Kaohsiung Chang Gung Memorial Hospital in southern Taiwan were enrolled. ...

Introduction. Urinary diversion is very often associated with urinary retention and urinary incontinence. In this study, a surgical modification during cystectomy with orthotopic ileal neobladder is presented. Material and Methods. Female patients enrolled in the study (n-24) were subjected to sacrocolpopexy during the operation. Apart from oncological control, the follow-up consisted of 1-hour...