Marine shales exhibit unusual behavior at low temperatures under anoxic gas flow. They generate catalytic gas 300 degrees below thermal cracking temperatures, discontinuously in aperiodic episodes, and lose these properties on exposure to trace amounts of oxygen. Here we report a surprising reversal in hydrocarbon generation. Heavy hydrocarbons are formed before light hydrocarbons resulting in ...

background: the innate immunity plays an important role in the host response to transplantation by toll-like receptors and results in development of acute allograft rejection. the aim of this study was to evaluate the association of tlr2 and cd14 (co-receptor) gene polymorphisms with acute rejection in kidney transplant recipients.   methods : the study was conducted in a population of 239 subj...

Gram-positive pathogens, such as Streptococcuspneumoniae, can have deleterious effects on both human and animal health. Antibiotics and antimicrobials have been developed to treat infections caused by such pathogens and to prevent food contamination. However, these strategies have been increasingly thwarted by the emergence of resistant bacteria strains. Thus, new methods for controlling Gram-p...

In this paper we present the current situation at the field of hypermedia data modelling. We list advantages and disadvantages of the most primitive hypermedia data model, i.e. the nodelink data model and the models of the second generation hypermedia, such as the Hyperwave data model and HM-Data Model. We believe that an introduction of a semantic hypermedia data model, called the HC-Data Mode...

Hepatocyte gap junction proteins, connexins (Cxs) 26 and 32, are down regulated during obstructive cholestasis (OC) and lipopolysaccharide hepatocellular cholestasis (LPS-HC). We investigated rat hepatic Cxs during ethynylestradiol hepatocellular cholestasis (EE-HC) and choledochocaval fistula (CCF) and compared them with OC and LPS-HC. Levels (immunoblotting) and cellular distribution (immunof...

The cellular prion protein (PrP(C)) is a GPI-anchored cell-surface protein. A small subset of PrP(C) molecules, however, can be integrated into the ER-membrane via a transmembrane domain (TM), which also harbors the most highly conserved regions of PrP(C), termed the hydrophobic core (HC). A mutation in HC is associated with prion disease resulting in an enhanced formation of a transmembrane fo...

Bimolecular reactions of phenyl-type radicals with the C4 and C5 hydrocarbons vinylacetylene and (methyl-substituted) 1,3-butadiene have been found to synthesize polycyclic aromatic hydrocarbons (PAHs) with naphthalene and 1,4-dihydronaphthalene cores in exoergic and entrance barrierless reactions under single-collision conditions. The reaction mechanism involves the initial formation of a van ...

BACKGROUND/AIMS Hypomagnesemia may induce hypercholesterolemia, but the contrary has not been described yet. Thus, magnesium homeostasis was evaluated in rats fed a cholesterol-enriched diet for 8 days. This study has a relevant clinical application if hypomagnesemia, due to hypercholesterolemia, is confirmed in patients with long-term hypercholesterolemia. METHODS Both hypercholesterolemic (...