نتایج جستجو برای: angiogenic activity

تعداد نتایج: 1147308  

2013
Hyun-Joo Jung Young-Wook Cho Hye-Won Lim Hojin Choi Dam-Jung Ji Chang-Jin Lim

This work aimed to assess some pharmacological activities of P. leptostachya var. asiatica Hara. The dried roots of P. leptostachya var. asiatica Hara were extracted with 70% ethanol to generate the powdered extract, named PLE. Anti-angiogenic activity was detected using chick chorioallantoic membrane (CAM) assay. In vitro anti-inflammatory activity was evaluated via analyzing nitric oxide (NO)...

2011
Sheng-Teng Huang Rong-Chi Yang Hsiao-Ting Wu Chao-Nin Wang Jong-Hwei S. Pang

BACKGROUND Ellagic acid (EA), a dietary polyphenolic compound, has been demonstrated to exert anti-angiogenic effect but the detailed mechanism is not yet fully understood. The aim of this study was to investigate whether the zinc chelating activity of EA contributed to its anti-angiogenic effect. METHODS AND PRINCIPAL FINDINGS The matrix metalloproteinases-2 (MMP-2) activity, a zinc-required...

Journal: :Biomaterials 2021

Mesenchymal stromal cells (MSCs) are characterized by a regulatory phenotype and respond promptly to the environmental signals modulating their secretory activity. An appropriate preconditioning may induce MSCs release secretomes with an enhanced regenerative potential. However, it fails take into account that composed both soluble factors extracellular vesicles (EVs), whose functions could be ...

Journal: :Haematologica 2000
F Di Raimondo M P Azzaro G Palumbo S Bagnato G Giustolisi P Floridia G Sortino R Giustolisi

BACKGROUND AND OBJECTIVES To study the role of some soluble factors in the process of angiogenesis that accompanies multiple myeloma (MM). DESIGN AND METHODS The concentrations of three well-known angiogenic peptides, vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and hepatocyte growth factor (HGF) were evaluated by an ELISA method. All of these factors were...

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