rabbitfish is economically valuable teleost species which lives in shallow coastalwaters. two species of rabbit fish have been recognized in southern sea of iran (persiangulf) as namely siganus sutor and siganus javus. in the current study, in order toinvestigate the histology of the annular ligament of the s. javus’ eye, the prepared sectionsof the eyes of twelve healthy specimens were studied...

introduction: there are differences in the pattern of the knee joint formation of the studied species. according to the small number of studies which focused chronologically on the avian knee histomorphogenetic events, its “morphogenetic pattern” is hard to be proposed. the present work was designed to identify the sequential events of the knee formation in the partridge embryo. regarding to di...

aim :  the aim of this study was to present the demographic and clinical characteristics of patients with gastric polypoid lesions and to study the histopathologic features of these lesions. background : the frequency of gastric polyps is gradually increasing due to the widespread use of endoscopic examinations. patients and methods : clinical and endoscopic features of 100 gastric polyposis pa...

since the uterine is a sensitive tissue to steroid hormones, the aim of the present study was to investigate the effects of 17β-estradiol (e2) and progesterone (p4) alone or in combination on morphological and morphometrically parameters of ovariectomized mouse uterus.adult virgin female mice (8-10 weeks old)were ovariectomized and treated with e2, p4, e2 followed by p4 and the oil vehicle alon...

introduction: lansoprazole is one of the proton pump inhibitor drugs widely used in the treatment of gastro-duodenal ulcers and disorders. however, there is not enough data about unexplored adverse effects of lansoprazole on the integrity of the placental barrier. therefore, the present study was conducted to determine whether placental structure could be affected by lansoprazole administration...

We explore autofluorescence endomicroscopy as a potential tool for real-time visualization of epithelial tissue microstructure and organization in a clinical setting. The design parameters are explored using two experimental systems--an Olympus Medical Systems Corp. stand-alone clinical prototype probe, and a custom built bench-top rigid fiber conduit prototype. Both systems entail ultraviolet ...

For many decades, we have relied on immortalised retinal cell lines, histology of enucleated human eyes, animal models, clinical observation, genetic studies and human clinical trials to learn more about the pathogenesis of retinal diseases and explore treatment options. The recent availability of patient-specific induced pluripotent stem cells (iPSC) for deriving retinal lineages has added a p...

Background and Purpose: Animal models are a necessity in the study of neuropathic pain, and much of what we know about pain comes from studies in mice and rats. However, very few basic discoveries have been translated so far from rodent models into effective pain therapy. This review presents the most important rat models used in basic pain research, discusses their limitations and recommends b...

1 Seren Gülşen Gürgen1, Oğuzhan Gürgen2, Günay Kırkım3, Hatice Efsun Kolatan4, Selhan Gürkan3, Görkem Eskiizmir5 1Celal Bayar University, School of Vocational Health Service, Department of Histology and Embryology, Manisa, 2Clinic of Otorhinolaryngology, Selçuk State Hospital, Izmir, 3Dokuz Eylül University, Faculty of Medicine, Department of Otorhinolaryngology, Izmir, 4Dokuz Eylül University,...

The sequential use of chemotherapy and surgery in the treatment of osteosarcoma developed in an empirical fashion without the benefit of investigations in animal models. The MGH-OGS murine osteosarcoma is a transplantable tumor that resembles the human disease with respect to histology, local invasiveness, metastatic characteristics, tumor ploidy, and its response to chemotherapy. We have used ...