نتایج جستجو برای: anion exchanger
تعداد نتایج: 44230 فیلتر نتایج به سال:
Folding and oligomerization of most plasma membrane glycoproteins, including those involved in ion transport, occur in the ER and are frequently required for their exit from this organelle. It is currently unknown, however, where or when in the biosynthetic pathway these proteins become functionally active. AE1 and AE2 are tissue-specific, plasma membrane anion transport proteins. Transient exp...
Reduced gastrointestinal HCO3- secretion contributes to malabsorption and obstructive syndromes in cystic fibrosis. The apical HCO3- transport pathways in these organs have not been defined. We therefore assessed the involvement of apical Cl-/HCO3- exchangers and anion conductances in basal and cAMP-stimulated duodenal HCO3- secretion. Muscle-stripped rat and rabbit proximal duodena were mounte...
A longevity gene called Indy (for 'I'm not dead yet'), with similarity to mammalian genes encoding sodium-dicarboxylate cotransporters, was identified in Drosophila melanogaster. Functional studies in Xenopus oocytes showed that INDY mediates the flux of dicarboxylates and citrate across the plasma membrane, but the specific transport mechanism mediated by INDY was not identified. To test wheth...
The partial purification of beef thyrotropin with the cation exchangers Amberlite IRC-50 (2, 3) and carboxymethyl (CM) cellulose (3, 4) has been previously reported. The preceding paper (5) describes the rechromatography on diethylaminoethyl (DEAE) cellulose of thyrotropin preparations assaying 20 U.S.P. units per mg which resulted in fractions apparently containing only those glycoproteins wit...
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