Cancer stem cells are involved in cancer establishment, progression, and resistance to current treatments. We demonstrated the in vitro and in vivo anti-breast cancer effect of bakuchiol in a previous study. However, the ability of bakuchiol to target breast cancer stem cells (BCSCs) and inhibit breast cancer metastasis remains unknown. In the current study, we used the cell surface markers CD4...

a new series of anti-cancer agents based on 1,2-diaryl-5,6-dihydropyrrolo[2,1-a]isoquinoline scaffold containing n,n-diethylamino ethoxy, piperidinyl ethoxy or morpholinyl ethoxy group at the para position of the c-2 phenyl ring were synthesized and their cytotoxic activities were assessed against several human cancer cell lines including mcf-7 (er positive breast cancer cell), mda-mb231 (er-ne...

background: women with the medical history of breast cancer constitute the biggest group of patients who survived cancer. despite the high rate of mastectomy after breast cancer in iran only limited patients elect reconstruction surgery. the aim of our study was to evaluate the rate of tendency to breast reconstruction (br) surgery among women with breast cancer who had mastectomy but not under...

Due to narrow therapeutic window of cancer therapeutic agents and the development of resistance against these agents, there is a need to discover novel agents to treat breast cancer. The antitumor activities of thymoquinone (TQ), a compound isolated from Nigella sativa oil, were investigated in breast carcinoma in vitro and in vivo. Cell responses after TQ treatment were assessed by using diffe...

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background: breast cancer is the most common cancer found in women, and screening is the best way to make an early diagnosis. the aim of this study was to determine the rate of screening mammography and related variables in the mammography center of mousavi hospital, located in zanjan, iran. methods: this was a prospective descriptive study. study sample size was 526 women who were selected by ...

background: electrochemotherapy is a relatively new technique in the treatment of skin metastases that are not amenable to conventional therapy. its use in breast cancer is now established in many european centers. methods: published literature of electrochemotherapy in terms of its scientific basis, current clinical practice of breast cancer treatment providers, as well as the future direction...

background: much research has widely been conducted into thyroid hormones levels following radiotherapy for breast cancer. consequently, in this study, we evaluated to relate the rate of thyroid hormones levels with the dose distribution among breast cancer patients. material and methods: thirty patients were treated with 4-field breast cancer radiotherapy. the dose volume histograms, the volum...

conclusions given the results, improving skills, training and awareness is necessary for women and emphasis on modified diet is recommended as a non-medical option for prevention of breast cancer. results the mean scores of feeding type in the patients with and without breast cancer was 56.14 and 66.25, respectively. results obtained from data analysis showed that there was statistically signif...

abstractwe are reporting a 43-year-old female breast cancer case with a solitary metastatic adenocarcinoma in clivus. this patient with a stage ii (t1n1m0) breast cancer history has been followed for 7 years.  modified radical mastectomy (mrm) and 6 courses chemotherapy with cmf (cyclophosphamide, metotrexate, 5fu) regimen were done for her at the time of diagnosis. also, she took tamoxifen twe...