Background and Objectives: Toxoplasmosis has become one of the more frequent opportunistic infections and the most common cause of focal brain lesions complicating the course of AIDS. However, there is a little information about the frequency of the toxoplasmosis in various regions of Iran. At the present study, we evaluated the prevalence of toxoplasmosis in patients with AIDS in Mashhasd (...

Women have emerged as the fastest growing human immunodeficiency virus (HIV) infected population worldwide, mainly because of the increasing occurrence of heterosexual transmission. Most infected women are of reproductive age and one of the greatest concerns for both women and their physicians is that more than 1,600 infants become infected with HIV each day. Almost all infections are a result ...

The urgent need for new anti-HIV/AIDS drugs is a global concern. In addition to obvious economical and commercial hurdles, HIV/AIDS patients are faced with multifarious difficulties associated with the currently approved anti-HIV drugs. Adverse effects, the emergence of drug resistance and the narrow spectrum of activity have limited the therapeutic usefulness of the various reverse transcripta...

From 1992 to 1995 we studied 232 (69% male, 87% Caucasian) anti-human immunodeficiency virus (anti-HIV) positive Brazilian patients, through a questionnaire; HIV had been acquired sexually by 50%, from blood by 32%, sexually and/or from blood by 16.4% and by an unknown route by 1.7%. Intravenous drug use was reported by 29%; it was the most important risk factor for HIV transmission. The alanin...

BACKGROUND Telbivudine is a potent inhibitor of hepatitis B virus (HBV) replication without anti-HIV type-1 (HIV-1) activity demonstrated in vitro; however, very few clinical data on HIV-1-infected patients are available at present. Because it represents a therapeutic option in HIV-1-HBV-coinfected patients who do not require antiretroviral therapy, we strictly monitored three HIV-1-HBV-coinfec...

Human Immunodeficiency Virus (HIV) is the etiological agent of Acquired Immunodeficiency Syndrome (AIDS). There are 2 types of HIV: HIV-1 and HIV-2. However, worldwide, predominant virus is HIV-1. The development of safe, effective and low cost anti-HIV drugs is among the top global priorities of drug development since the disease is not yet curable, significant toxicity of available anti-HIV d...

BACKGROUND Amebic liver abscess is a tropical disease with a wide spectrum of clinical presentations. Given the often nonspecific nature of the complaints related to amebic abscess, a retrospective review of patients with confirmed disease to recognize the most common patterns of presentation is useful. Here, we study the clinical presentations of 62 Thai patients with amebic liver abscess. We ...

Alterações cognitivas associadas ao HIV são relativamente comuns. Assim, o diagnóstico precoce do torna-se importante para a prevenção comprometimento cognitivo que, por sua vez, interfere na qualidade de vida dos indivíduos. O objetivo foi avaliar desempenho indivíduos infectados pelo HIV/Aids. Trata-se um estudo transversal. Participaram adultos com 50 anos ou mais, HIV/Aids, assistidos no Se...