نتایج جستجو برای: anti human globulin

تعداد نتایج: 1935707  

Journal: :Journal of Biological Chemistry 1950

Journal: :The Journal of Experimental Medicine 1960
Vera J. Stecher G. Jeanette Thorbecke

Gamma globulin formation in vitro by various tissues was studied using the incorporation of C(14)-L-lysine into a protein precipitable by a specific anti rabbit gamma globulin serum prepared in a sheep. It was demonstrated that the rate of gamma globulin formation in similar numbers of spleen cells is much higher if taken from an immunized rabbit at the height of antibody formation than that in...

Journal: :Applied microbiology 1972
H D Hutchinson D W Ziegler

A simplified, indirect radioimmunoassay is described for Escherichia coli, vaccinia virus, and herpesvirus. The antigens were affixed to glass cover slips; thus both the primary and secondary reactions take place on the cover slips, and the unbound antiserum is easily separated from the bound antiserum by rinsing. Rabbit or human immune sera were reacted with the antigens, and the primary immun...

Journal: :Journal of immunology 2003
Esther M Yoo Letitia A Wims Lisa A Chan Sherie L Morrison

Unlike IgA and IgM, IgG has not yet been shown to form covalent polymers. However in the presence of specific Ag, murine IgG3 has been shown to polymerize through noncovalent interactions. In contrast to the noncovalent oligomers found with murine IgG3, we have detected covalent dimers in three different recombinant human IgG2 Abs produced in myeloma cells. Both IgG2,kappa and IgG2,lambda can f...

Journal: :The Tohoku journal of experimental medicine 1969
T Kuroyanagi H Sugiyama

The direct anti-globulin test was performed at random on 310 hospitalized patients with various diseases. Thirty-three patients were positive to anti-globulin test without any evidence of manifest autoimmune hemolytic anemia. Hematologic and erythrokinetic studies on these patients with latent autoim mune hemolytic syndrome revealed that their slight anemia was secondary anemia due to their bas...

Journal: :Journal of clinical pathology 1960
E J FIELD A RIDLEY

A simple anti-gamma-globulin consumption test for use in suspected Hashimoto's disease is described. Results in cases with positive and negative tanned red-cell tests are described.

Journal: :The Journal of Experimental Medicine 1970
N. Abramson A. F. Lo Buglio J. H. Jandl R. S. Cotran

Red cells coated with IgG globulin were bound firmly to human mononuclear cells and formed rosettes. Rosette formation occurred when red cells were coated with IgG attached either immunologically (anti-D, anti-penicillin, or Donath-Landsteiner antibodies) or nonimmunologically with chromic chloride; no attachment was observed with cells coated with albumin. Rosette formation was blocked by pret...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2006
Zhaochun Chen Patricia Earl Jeffrey Americo Inger Damon Scott K Smith Yi-Hua Zhou Fujuan Yu Andrew Sebrell Suzanne Emerson Gary Cohen Roselyn J Eisenberg Juraj Svitel Peter Schuck William Satterfield Bernard Moss Robert Purcell

Chimpanzee Fabs against the B5 envelope glycoprotein of vaccinia virus were isolated and converted into complete mAbs with human gamma 1 heavy chain constant regions. The two mAbs (8AH8AL and 8AH7AL) displayed high binding affinities to B5 (Kd of 0.2 and 0.7 nM). The mAb 8AH8AL inhibited the spread of vaccinia virus as well as variola virus (the causative agent of smallpox) in vitro, protected ...

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