In this study, antibacterial, antifungal, antimycobacterial, cytotoxic, antitumor, cardiovascular, antifeedant, insecticidal, antileishmanial and some other single activities of diterpenoids and norditerpenoids isolated from Turkish Lamiaceae plants, are reviewed. The diterpenoids were isolated from species of Salvia, Sideritis, and Ballota species growing in Anatolia. Fifty abietanes, ten kaur...

In the present study, various amide derivatives of sulfanilamide, sulfamethoxazole, sulfadiazine, dapsone and isoniazid have been synthesized by condensing them with appropriate 4-oxo-4-(4-substituted phenyl)butanoic acid moiety. The compounds have been evaluated for their antiinflammatory, ulcerogenic and antibacterial activities. Their structures were established on the basis of elemental ana...

A series of 5-(pyridin-4-yl)-3-thioacetamide-1,2,4-triazoles (4a-o), was synthesized, characterized and evaluated for screening antibacterial and antifungal activities on microorganisms, respectively on five bacteria and and candida tropicalis. The structures of original compounds were confirmed by analytical and spectroscopic (FT-IR, H NMR and C NMR) methods and elemental analysis. Both the an...

The reaction of p-bromoanilino acetohydrazide(II) with aromatic aldehydes in alcohol yielded 2-[4-bromo aniline] N-substituted benzylidine hydrazides (IIIa-IIIj), which in presence of yellow mercuric oxide and iodine in DMF, yielded corresponding 4-bromo[(N-5-substituted 1,3,4 oxadiazole-2 -yl)methyl]aniline (IVa-IVj). Structures of the compounds synthesized were confirmed by IR, (1)HNMR and MA...

The objective of this study is to determine the tyrosinase inhibition and antibacterial activities against the pathogenic bacteria in the oral cavity of the mangosteen pericarp extract. The results showed that the mangosteen pericarp extract inhibited the tyrosinase enzyme at IC50 = 67 ng/ml. Furthermore, the mangosteen pericarp extract also exhibited the antibacterial activities against the pa...

Mixed ligand complexes of transition metal with 8-quinolinols and 5-Alkoxumethyl-8-quinolinol have been prepared. Structural, spectroscopic and thermal properties have been studied on the basis of infrared spectra, Mass spectra, NMR spectra, electronic spectra, and elemental analyses. Also their antibacterial activities against Gram – ve (Escherichia coli and Ps. Aeruginosa Bacillus subtilis) a...

traditionally used for treatment of several diseases including its theoretic use in microbial We have isolated three flavonoids (Artochamin C, 5'Hydroxycudraflavone A and Dihydrocudraflavone B) based on bioactivity guided isolation. All compounds showed significant antibacterial activities against Escherchia coli, Staphylococcus aureus, Klebsiella pneumoniae and Bacillus subtilis. Artochamin C ...

Propolis is one of the complex, but valuable, bio-sources for discovering therapeutic compounds. Diterpenes are organic compounds composed of four isoprene units and are known for their biological and pharmacological characteristics, such as antibacterial, anticancer, and anti-inflammatory activities. Recently, advancements have been made in the development of antibacterial and anticancer leads...

Effects of wiping copper-alloyed stainless steel surfaces with disinfectants to remove protein surface contaminants and re-establish their antibacterial activities were quantitatively studied. Disinfectants used were sodium hypochlorite aqueous solutions and ethyl alcohol aqueous solutions. Wiping with NaOCl aqueous solutions effectively removed protein surface contaminants. Ethyl alcohol aqueo...

A series (7a-7k) of aliphatic amide bridged 4-aminoquinoline clubbed 1,2,4triazole derivatives were designed on the basis of field alignment and mapping and finally synthesized via six step synthesis protocol. The antibacterial activities of all the synthesized molecules were performed on different gram positive and gram negative bacterial strains. Compound 7a, 7d and 7h were found most active ...