The antibacterial activity and mechanism of berberine against Streptococcus agalactiae were investigated in this study by analyzing the growth, morphology and protein of the S. agalactiae cells treated with berberine. The antibacterial susceptibility test result indicated minimum inhibition concentration (MIC) of berberine against Streptococcus agalactiae was 78 μg/mL and the time-kill curves s...

Some new Zn(II) and Cu(II) complexes [Cu(L1)(OAc)2]∙H2O, [Cu(L1)(NO3)H2O]∙NO3∙3.5H2O, [Zn(L1)(NO3)2]∙4.5H2O, [Zn(L1)(OAc)2(H2O)2]∙3H2O, [Cu2(L2)(OAc)4]∙2H2O∙2DMF, [Cu(L2)2]∙2NO3∙1.5DMF∙H2O, [Zn(L2)2(NO3)2]∙DMF and [Zn2(L2)(OAc)4(H2O)4]∙5H2O; L1 = 2-[2-(2-methoxyphenyl)hydrazono]cyclohexane-1,3-dione and L2 = 2-[2-(3-nitrophenyl)hydrazono]cyclohexane-1,3-dione were synthesized and characterized ...

The article provides data on the isolation and identification of pathogen S. Pullorum from pathological material chickens. With further study tinctorial, cultural-morphological biological properties pathogen. susceptibility Salmonella pullorum to broad-spectrum antibacterial drugs such as cephalosporins carbopenems was studied determine drug choice for improving treatment prevention avian bacte...

General practitioners (GPs) may lack specialist microbiological knowledge, making it difficult for them to use documents concerning antibacterial spectra provided by French health authorities. We have developed a tool to help GPs to compare antibacterial spectra, based on an ontology of bacteria generated using OWL-DL language. This tool makes it possible to search for information concerning th...

Streptococcus pyogenes is commonly believed to be resistant to trimethoprim-sulfamethoxazole (SXT), resulting in reservations about using SXT for skin and soft tissue infections (SSTI) where S. pyogenes is involved. S. pyogenes' in vitro susceptibility to SXT depends on the medium's thymidine content. Thymidine allows S. pyogenes to bypass the sulfur-mediated inhibition of folate metabolism and...

BACKGROUND Staphylococcus aureus can cause severe infections, including bacteremia and sepsis. The spread of methicillin-resistant Staphylococcus aureus (MRSA) highlights the need for novel treatment options. Sodium new houttuyfonate (SNH) is an analogue of houttuynin, the main antibacterial ingredient of Houttuynia cordata Thunb. The aim of this study was to evaluate in vitro activity of SNH a...

The present study was carried out to investigate antibacterial activity of ceftobiprole and vancomycin invitro and in-vivo after inducing osteomyelitis in rabbit by administration of Methicillin Resistant Staphylococcus Aureus (MRSA). Part I, evaluation is done in-vitro by using hot plate method for appearance zone of inhibition and Minimum Inhibitory Concentration (MIC) against (MRSA). Antibac...

Antibacterial and antifungal activity of N-phthaloylamino acid hydroxamates [C6H4(CO)2N-X-CONHOH, X=amino acid residues of glycine, beta-alanine or D-phenylglycine], was examined against 44 strains of Gram-positive and Gram-negative bacteria, and 10 species of yeasts. The level of antimicrobial activity was established using the in vitro agar assay and the standard broth dilution susceptibility...

One of the characteristics of the host defense of insects is the rapid synthesis of a variety of potent antibacterial and antifungal peptides. To date, seven types of inducible antimicrobial peptides (AMPs) have been characterized in Drosophila. The importance of these peptides in host defense is supported by the observation that flies deficient for the Toll or Immune deficiency (Imd) pathway, ...

Ethanolic extract of fresh leaves of Acalypha wilkesiana was screened for its phytochemical and invitro antibacterial properties on four clinical isolates Staphylococcus aureus, Escherichia coli , Shigella sp , and Klebsiella pneumonia. The disc diffusion technique was used to assay for the antimicrobial properties. The results showed that the extract of concentrations between 50mg/ml to 200mg/...