background :highserum level of cancer antigen 15.3 (ca15.3) has been reported in some malignant and nonmalignant conditions including thalassemia major which could have been resulted from ineffective erythropoiesis. we aimed to evaluate the serum level of ca15.3 in carriers of beta-thalassemia by comparing them with cancer patients and healthy individuals.   methods : this cross-sectional study...

background:non-melanoma skin cancer (nmsc), the most prevalent types being squamous cell carcinoma (scc) and basal cell carcinoma (bcc), is the most common type of malignancy in human beings. these neoplasms are more frequent in the elderly and fair skinned people and mainly occur on sun-exposed sites of the body. ultraviolet b (uvb) has a well-known effect in induction and promotion of growth ...

background: klebseilla pneumoniae causes urinary tract infections, nosocomial pneumonia and intra-abdominal infections. capsular antigens are considered to be the ultimate virulence determinants. among 77 capsular serotypes of k. pneumoniae, serotypes k1 and k2 are the most virulent ones in humans. objectives: we designed a pcr method for detection of capsular serotypes k1 and k2 of k. pneumoni...

background: hla-g gene contains 15 alleles including a null allele, hla-g*0105n. previous studies have shown that hla-g*0105n does not encode the complete hla-g1 or hla-g5 isoforms but encodes a functional hla-g protein with the ability to in-hibit nk cell cytolysis. thus, although the biological functions of hla-g1 and hla-g5 proteins are abrogated, other isoforms such as hla-g2 can replace th...

hydatid cyst is an important and zoonotic infection caused by cystic stage of echinococcus granulosus. it is a major and economic problem in most areas of the world that livestock are kept such as iran. in this study, a total of 111 buffalo,s sera from center of buffalo sperm preparation (cbsp), orumia (west azarbayjan province, iran, 2003) were examined for the presence of hydatidosis by using...

background and objective: prostate cancer is a prevalent disease around the world. the prostatic specific antigen (psa) test has recently proved itself as a useful method for the diagnosis and examination of patients with prostatic cancer. the objective of this study was to compare the stability of free psa and total psa in different storage settings. materials and methods: samples were obtaine...

biomolecular behavior of tumor cells has become attractive to investigators. p53 as an oncosuppresor gene has been core of various studies and ki67 is a nuclear protein involved in proliferation process. stopping of onco-suppressor function theoretically allows proliferative system to get out of any control. in this case-control study we evaluated 50 patients with non small cell lung cancer, co...

cystoscopy and urinary cytology are currently the basis for diagnosis and ‎follow-up of bladder tumors. research to find a sensitive and specific tumor ‎marker for diagnosis of bladder tumor is actively underway, however, due to low sensitivity ‎and high cost of cytology. this cross-sectional study was performed in 65 patients to evaluate whether urinary bladder ‎cancer (ubc) antigen level can ...