نتایج جستجو برای: antigen modification
تعداد نتایج: 324768 فیلتر نتایج به سال:
Sialic acids are negatively charged nine-carbon carboxylated monosaccharides that often cap glycans on glycosylated proteins and lipids. Because of their strategic location at the cell surface, sialic acids contribute to interactions that are critical for immune homeostasis via interactions with sialic acid-binding Ig-type lectins (siglecs). In particular, these interactions may be of importanc...
Cross-presentation is an important mechanism by which DCs present exogenous antigens on MHC-I molecules, and activate CD8 1 T cells, cells that are crucial for the elimination of tumors. We investigated the feasibility of exploiting the capacity of the mannose receptor (MR) to improve both cross-presentation of tumor antigens and Th polarization, processes that are pivotal for the anti-tumor po...
Carcinoembryonic antigen, an apical membrane glycoprotein expressed in normal human colonic epithelial cells, colonic polyps, tumor, and tissue culture cell lines originating from colonic adenocarcinomas, is generally considered to have a molecular weight of 180,000. Using sodium dodecyl sulfate-polyacrylamide gel electrophoresis associated with immunoprecipitation or immunoblotting with both m...
For cancer immunotherapy via tumor antigen vaccination in combination with an adjuvant, major challenges include the identification of a particular tumor antigen and efficient delivery of the antigen as well as adjuvant to antigen-presenting cells. In this study, we proposed an efficient exosome-based tumor antigens-adjuvant co-delivery system using genetically engineered tumor cell-derived exo...
We devised a new method for measuring responses of canine airway musculature, bronchosecretion and bronchial vasculature simultaneously, in situ, and investigated the effects of prostaglandins F2alpha and E2 and antigen-antibody reaction by using this model. The right bronchial artery was perfused with blood at a constant flow under artificial respiration. Airway musculature response was measur...
background: anaphylactic reactions, such as urticaria, edema, respiratory symptoms, and anaphylactic shock often complicate the course of cystic echinococcosis (ce). methods: to investigate the role of the ige immunoreactive antigen 5 (ag 5) in the sero-positive patients with ce, we determined n-terminal of 57 kda subunit of ag5 responsible for ige and c-terminal of this active antigen related ...
تجزیه و تحلیل تراکنش بین سلول های ایمنی بدن و واکسیناسیون جهت درمان سرطان به وسیله یک مدل ریاضی تبیین شده توسط مشتقات مرتبه کسری در این تحقیق یک مدل ریاضی جهت تبیین تراکنش بین سلول های ایمنی و غده سرطانی، که به صورت یک دستگاه دینامیکی است، را مورد تجزیه و تحلیل قرار می دهیم. در این مدل تأثیر سلول های سیستم ایمنی بدن و برهم کنش بین آن ها بر روی دوره های نهفتگی و بازگشت بیماری سرطان مورد توج...
Guinea pigs intranasally dusted with ragweed pollen (RW) for one month went into anaphylaxis in ragweed extract aerosol (RWEA). Animals which received RWEA pretreatment for one month before nasal dusting with RW pollen were nonresponsive to RWEA. The purpose of this study was to define the mechanism of nonresponsiveness. The protocol for producing either sensitivity or nonresponsiveness was app...
Convergent evolution dictates that diverse groups of viruses will target both similar and distinct host pathways to manipulate the immune response and improve infection. In this study, we sought to leverage this uneven viral antagonism to identify critical host factors that govern disease outcome. Utilizing a systems-based approach, we examined differential regulation of IFN-γ-dependent genes f...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید