Objective: The study is to evaluate the possible genotoxic and antigenotoxic potential of Lagenandra toxicaria rhizome methanol extract using Allium cepa root tip assay.
 Methods: was prepared Soxhlet apparatus. A. roots were treated with various concentrations at different time points stained aceto-orcein. mitotic index (MI) calculated.
 Results: A significant decrease in MI increase...

Ayurveda is an ancient science of life that uses a wide range formulations or herbal compounds to treat various diseases. Each drug must be scientifically, pre-clinically, and clinically evaluated in order gain global acceptance. As part the safety evaluation process, regulatory authorities around world require data on new genotoxic potential.MusalyadiChurna(MSDC) classical Ayurvedic formulatio...

The concept of polyherbalism has been highlighted in , an Ayurvedic literature dating back to 1300 AD. Polyherbal formulations enhance the therapeutic action and reduce concentrations single herbs, thereby reducing adverse events. In present study, clastogenic effect carwin capsuleshas evaluated against cyclophosphamide (CP)-induced chromosomal aberrations bone marrow cells mice. Genotoxicity w...

Bu çalışmada, tıbbi öneme sahip bir bitki olan ve pek çok hastalığın tedavisinde yaygın olarak kullanılan Althaea officinalis L. bitkisinin antigenotoksik etkisi çalışıldı. amaçla somatik mutasyon rekombinasyonu ölçen in vivo test Drosophila kanat benek testi (SMART) kullanıldı. Mitomisin C (MMC) mutajenine karşı A. araştırıldı. Çalışmalar sonrasında, kurutulmuş herbasının 5 mg, 15 mg 45 mg’lık...