Hypertension is one of the significant risk factors for cardiovascular disease and can lead to complications. Uncontrolled hypertension vascular endothelial dysfunction other complications disease. This study aimed determine effect turmeric rhizome (Curcuma longa L.) in extracts fractions on a hypertensive rat’s model induced by L-NAME 40 mg/kg three weeks an acute toxicity extract. Antihyperte...

A genetic alteration in the adducin genes is associated with hypertension and up-regulation of the expression of renal Na, K-ATPase in Milan-hypertensive (MHS) rats, in which increased ouabain-like factor (OLF) levels are also observed. PST 2238, a new antihypertensive compound that antagonizes the pressor effect of ouabain in vivo and normalizes ouabain-dependent up-regulation of the renal Na-...

Enzymatic hydrolysis of food proteins can release peptides able to exert different biological activities. Among the bioactive peptides known so far, those with angiotensin converting enzyme (ACE)inhibitory properties are receiving special attention due to their potential beneficial effects in the treatment of hypertension. In previous work we identified active peptide sequences that derive from...

Individuals with rheumatoid arthritis , systemic lupus erythematosus or gout have increased risk of cardiovascular disease (CVD) compared the general population. This relates to a combination traditional factors and disease-specific factors. Screening for CVD is important because contributes significant morbidity mortality. Management includes tight control activity reduce inflammation, but car...

abstract  introduction: hypertension is a major cause of cardiovascular disease and the prevalence of hypertension shows a linear increase with aging so that it increases by 10 percent every 10 years. this study was conducted to investigate the causes of uncontrolled blood pressure in people aged over 65 years. methods: this descriptive case-control study was conducted at isfahan amin hospital ...