used as chemoprophylaxis in areas of the world with chloroquine-resistant P. falciparum. The authors should also have included chloroquine in their recommendations, since pyrimethamine-sulfadoxine is insufficient prophylaxis in areas where P. falciparum and P. vivax co-exist. The text contains numerous typographical errors and the table on antimicrobial prophylaxis is difficult to read. The aut...

Abstract Background Antimicrobial use in Irish older persons residential care facilities (OP RCFs) is higher than other European countries. In 2020/21, for the first time, an antimicrobial pharmacist (AMP) was appointed to each community healthcare organization (CHO) monitor, develop and promote stewardship settings. Objectives To establish baseline antibiotic use, tools OP RCFs, best practice ...

introduction: the management and use of antimicrobial drugs has clinical, economic, and environmental implications. in many countries, antimicrobial drugs are the most frequently prescribed therapeutic agents. therefore, health-care policy should focus on how to establish a rational attitude toward antibiotics. this study was performed to investigate antibiotic usage as a prophylactic regimen i...

OBJECTIVE To assess the effectiveness of a protocol for prevention of surgical site infection (SSI) in colorectal surgery. PATIENTS AND METHODS Evaluation of 2 cohorts of patients undergoing colon and rectal surgery in a tertiary public hospital: A historical cohort (2008-2011) and a prospective one (after the implementation of the program in 2012). The main measures established were: Adequac...

More than a million hip replacements are carried out each year worldwide, and the number of other artificial joints inserted is also rising, so that infections associated with arthroplasties have become more common. However, there is a paucity of literature on infections due to haematogenous seeding following dental procedures. We reviewed the published literature to establish the current knowl...

The incidence of transient bacteremia after tooth extraction without antimicrobial prophylaxis has been reported was high as 69.2%; that with intravenous ampicillin as 4.2% (1, 2). Currently, we tested a regime of vancomycin that was recommended by the American Heart Association as prophylaxis for oral surgery patients who were allergic to penicillin and evaluated its effectiveness. Before the ...

Infections are a major cause of morbidity and mortality after lung transplantation. Pretransplant assessments for infection risk and immunization updates may help reduce posttransplant infections. In addition careful choice of posttransplant prophylaxis for cytomegalovirus and fungal infections is critical. Because of the potential association of infections such as respiratory viral infections ...

Methods A study was performed in October 2010 in a General Surgery Clinic in a hospital in Belgrade and in February 2011 in seven surgery clinics in a hospital in Novi Sad. Data concerning preoperative health status, type and duration of surgery and parameters of antimicrobial prophylaxis (drug choice, timing of first dose, number of dosis and duration of prophylaxis) were collected. Rresults a...

BACKGROUND Little generalizable information is available on the outcomes of children diagnosed with bladder and bowel dysfunction (BBD) after a urinary tract infection (UTI). Our objectives were to describe the clinical characteristics of children with BBD and to examine the effects of BBD on patient outcomes in children with and without vesicoureteral reflux (VUR). METHODS We combined data f...

BACKGROUND The reliability of patient-reported penicillin allergies has been disputed. A Drug Allergy Clinic (DAC) was established at our institution in combination with an electronic best practice alert (BPA) in the Orthopedic Clinic. Joint arthroplasty patients with a reported history of beta-lactam allergy (HOBA) were preoperatively referred via the BPA to the DAC. The purpose of this study ...