نتایج جستجو برای: antiproliferative activity

تعداد نتایج: 1139196  

Journal: :F1000Research 2022

Background: Several studies have shown that active compounds of Asclepias subulata (cardenolides) antiproliferative effect on human cancer cells. Cardenolides isolated from A. can be used as chemical markers to elaborate phytopharmaceutical preparations. The aim this work was evaluate the a standardized...

2015
Zoriţa Diaconeasa Loredana Leopold Dumitriţa Rugină Huseyin Ayvaz Carmen Socaciu

The present study was aimed at evaluating the antiproliferative potential of anthocyanin-rich fractions (ARFs) obtained from two commercially available juices (blueberry and blackcurrant juices) on three tumor cell lines; B16F10 (murine melanoma), A2780 (ovarian cancer) and HeLa (cervical cancer). Individual anthocyanin determination, identification and quantification were done using HPLC-MS. A...

Journal: :Chemotherapy 2010
Nadejda Valiaeva Julissa Trahan Kathy A Aldern James R Beadle Karl Y Hostetler

BACKGROUND/AIMS 9-[2-(phosphonomethoxy)ethyl]guanine (PMEG) is one of the most active antiproliferative compounds in a series of acyclic nucleoside phosphonates and is active in intraperitoneal P388 tumors in mice. METHODS We synthesized octadecyloxyethyl (ODE) and hexadecyloxypropyl esters of PMEG and compared their antiproliferative activity with unmodified PMEG in primary human fibroblasts...

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