The present study was aimed to develop the Glimepiride (GLM) loaded nanosuspension by different methods for increasing solubility of GLM. Twelve formulations were prepared combination method (FG), which included antisolvent precipitation followed sonication (Method 1) selecting drug and polymer in ratio 1:10, 1:20 1:30. Further 6 nanoprecipitation (Fg) 2) using polymers like polyvinyl pyrolidon...

Low-temperature processed carbon-based perovskite solar cells have received great attention due to low-cost, high stability, and simple preparation processes that can be employed in large-scale manufacturing. Carbon paste is deposited by techniques such as doctor blading or screen printing. However, solvents from this damage the underlying layers resulting poor performance of cells. Furthermore...

Polyphenols or phenolic compounds are groups of secondary metabolites widely distributed in plants and found in olive mill wastewater (OMW). Phenolic compounds as well as OMW extracts were evaluated in vitro for their antimicrobial activity against Gram-positive (Streptococcus pyogenes and Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli and Klebsiella pneumoniae). Most of th...

BACKGROUND In recent times, it has been proposed to classify endodontic files as single-use items due to a perceived inability to adequately clean the instruments. The purpose of the present study was to quantify the surface debris on files removed from the manufacturer's packaging, and after cleaning using an ultrasonic bath or a thermal disinfector. METHODS Stainless steel and rotary nickel...

in this study, confined impinging liquid jets are used to produce nanoparticles of carbamazepine (cbz). the effect of operating parameters, such as the kind of solvent,cbz concentration, flow rate of solution and antisolvent on particle size, are experimentally investigated. the scanning electron micrograph (sem) photomicrographs show that nanodrug with smaller particle is achievable by using s...

Tenderness is one of the most appreciated quality characteristics in beef by consumers. Meat aging recognized natural methodology to improve tenderness beef. The current study was designed evaluate if ultrasonication able simulate (ultrasonication alone) or grant an additional effect (aging plus ultrasonication) two different methods (dry and wet) on sensory profile Longissimus lumborum muscle....

in this work, mn ferrite nanopowders were prepared by co-precipitation method and were characterized. phase identification of the nanopowders was performed by x-ray diffraction method and the mean particle size of the nanopowders was calculated by scherrer's formula, using necessary corrections. magnetic parameters of the prepared nanopowders were measured by a vibrating sample magnetomete...

Systematic nonlinear optimisation is a valuable tool towards evaluating the performance of conceptual Continuous Pharmaceutical Manufacturing (CPM) flowsheets. This study considers total cost minimisation of multiple plausible design choices and eight candidate antisolvents for the continuous recovery of artemisinin (a potent antimalarial Active Pharmaceutical Ingredient/API) via continuous cry...

Because of minimal data available on folate analysis in dried matrix spots (DMSs), we combined the advantages of stable isotope dilution assays followed by LC-MS/MS analysis with DMS sampling to develop a reliable method for the quantitation of plasma 5-methyltetrahydrofolic acid in dried blood spots (DBSs) and dried plasma spots (DPSs) as well as for the quantitation of whole blood 5-methyltet...

Near-IR (NIR) emitting semiconducting polymer dots (Pdots) with ultrabright fluorescence have been prepared for specific cellular targeting. A series of π-conjugated polymers were synthesized to form water dispersible multicomponent Pdots by an ultrasonication-assisted co-precipitation method. By optimizing cascade energy transfer in Pdots, high-intensity NIR fluorescence (φ = 0.32) with tunabl...