BACKGROUND Aortic valve area (AVA) estimation in patients with aortic stenosis may be obtained using several methods. This study was undertaken to verify the cardiovascular magnetic resonance (CMR) planimetry of aortic stenosis by comparing the findings with invasive catheterization, transthoracic (TTE) as well as tranesophageal echocardiography (TEE) and anatomic CMR examination of autopsy spe...

BACKGROUND Although aortic valve replacement can be performed at an acceptable risk level in selected patients with left ventricular systolic dysfunction and low-output, low-gradient aortic stenosis, not all patients presenting with these hemodynamics will benefit from the operation. Some patients may have only mild aortic stenosis, despite a small calculated valve area. We report on the clinic...

IN THE STUDY of hemodynamics in aortic stenosis until the last decade more or less indirect methods were used, such as electrocardiography and phonocardiography, and direct and indirect pulse tracings. At best the results would confirm a clinical diagnosis but often were of little help in the surgical evaluation of the valvular defect. Only after the introduction of left-sided heart catheteriza...

Current medicine has displayed a trend toward less interfering techniques but more invasive surgical approaches in older patients with more comorbidities. In this population, the prevalence of symptomatic cardiac disease including aortic stenosis is increased. More than 25 years have elapsed since severe aortic stenosis was identified as an independent, important risk factor for patients underg...

AIMS Supravalvar aortic stenosis is a rare form of left ventricular outflow tract obstruction that is often progressive in childhood. Little data are available on outcomes in the adult population. Our aim was to define cardiac outcomes in adults with supravalvar aortic stenosis. METHODS AND RESULTS This is a multicentre retrospective study of cardiac outcomes in adults (≥18 years) with suprav...

Senile degenerative valvular aortic stenosis affects approximately 2% of the population over the age of 65. Aortic stenosis impedes left ventricular emptying and increases left ventricular wall stress, which leads to elevation of brain natriuretic peptide (BNP) levels. Aortic stenosis progresses slowly, allowing the left ventricle to develop concentric hypertrophy, which normalizes wall stress....

PURPOSE This paper proposes a model to measure the cardiac output and stroke volume at different aortic stenosis severities using a fluid-structure interaction (FSI) simulation at rest and during exercise. METHODS The geometry of the aortic valve is generated using echocardiographic imaging. An Arbitrary Lagrangian-Eulerian mesh was generated in order to perform the FSI simulations. Pressure ...

in Aortic Stenosis " 1 with great interest and would like to commend the authors for producing novel coronary wave intensity data in the aortic stenosis population. The microcirculatory decompression (suction) wave was reported to increase in proportion to the severity of aortic stenosis (rϭ0.59, Pϭ0.05), a change opposite to that which was reported previously by the same authors in patients wi...

Griffin BP. Effect of hydroxymethylglutaryl coenzyme A reductase inhibitors on the progression of calcific aortic stenosis. Circulation 2001;104:2205–2209. 8. Bellamy MF, Pellikka PA, Klarich KW, Tajik AJ, Enriquez-Sarano M. Association of cholesterol levels, hydroxymethylglutaryl coenzymeA reductase inhibitor treatment, and progression of aortic stenosis in the community. J Am Coll Cardiol 200...

27 Baltazar RF, Go EH, Benesh S, Mower M. Case report: myocardial ischemia: an overlooked substrate in syncope of aortic stenosis. AmIMed Sci 1992;303:105-8. 28 Dineen E, Brent BN. Aortic valve stenosis: comparison of patients with to those without chronic congestive heart failure. AmJ Cardiol 1986;57:419-22. 29 Villari B, Campbell SE, Hess OM, Mall G, Weber KT, Krayenbuehl HP. Effect of aortic...