BACKGROUND The frequency of recurrent aphthous stomatitis (RAS), the most common oral mucosa lesions seen in primary care, is up to 25% in the general population. However, there has been no optimal therapeutic approach. Our objective was to confirm our previous clinical observation of the beneficial treatment of RAS with vitamin B(12). METHODS A randomized, double-blind, placebo-controlled tr...

BACKGROUND Behçet's disease (BD) is a chronic, relapsing, systemic vasculitis of unknown aetiology. The involvement of oral mucosal surfaces represents the onset feature of the disease in the majority of patients. OBJECTIVE The aim of this study was to evaluate the periodontal status of BD patients and then compare with recurrent aphthous stomatitis (RAS) patients and healthy controls. We als...

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Background: Aphthous stomatitis is a painful and often inflammatory condition. Objective of the study to evaluate safety efficacy Arimu mouth ulcer gel (AHPL/ AYTOP/2014A) in subjects suffering from aphthous ulcers. Methods: This compared effect (Group I), with sponsors other gels II, Group III), marketed Ayurvedic formulation IV), conventional preparation V). Subjects were advised apply given ...

The aim of this work was to investigate the association between recurrent aphthous stomatitis (RAS) and salivary thiocyanate levels. The sample comprised men and women of age ranging from 15 to 55 years, who were allocated to four groups: 28 patients in RAS active phase (group 1); 28 patients in RAS remission phase (group 2); 29 smokers (group 3); 26 non-smokers without RAS (group 4). Samples o...