Background: Colon cancer is one of the most diagnosed cancers in modern world. Chemotherapy relevant treatments for colon cancer, but this method treatment has severe and sometimes irreversible side effects. Therefore, alternative with fewer effects are highly considered. Natural herbal medicine been proven to be a great source these methods. Objectives: This study aimed investigate anti-prolif...

C-phycocyanin, which is a major biliprotein of the blue-green algae, has been shown to possess cyclooxygenase-2 inhibitory activity. We have studied the effect of phycocyanin on a rat histiocytic tumor line. AK-5 cells are induced into apoptotic death program when treated with phycocyanin, which involves the activation of caspase-3. Phycocyanin-mediated apoptotic death is induced through the ge...

AIMS In this study we followed the effect of menopause and estrogenic replacement therapy on the proliferative and apoptotic activity of the bladder urothelial cells. METHODS The experimental model of menopause was reproduced using a standard protocol of bilateral ovariectomy in rats, estrogen replacement therapy being achieved by systemic administration of hexestrol diacetate for six weeks. ...

objective(s) the effect of berberis vulgaris aqueous extract in hepatocarcinogenic rats was studied to investigate the apoptotic and sodium, potassium elements properties. a loss of both intracellular potassium and sodiumoccurs when apoptotic cells shrink and prior to the loss of membraneintegrity. materials and methods forty-eight sprague dawley rats were randomly divided into 2 groups, normal...