Introduction: Lung resection surgery is a challenge to thoracic surgeons. Outcome of surgery depends on patients’ tolerance to reduced lung volume and hemodynamic alterations. The present study aimed to investigate the changes in blood gases and hemodynamic parameters in patients undergoing lung resection surgery and the associated clinical implications. Materials and methods: This study includ...

Cerebral blood flow (CBF) is highly regulated by changes in arterial PCO 2 and arterial PO 2. Evidence from animal studies indicates that various vasoactive factors, including release of noradrenaline, endothelin, adrenomedullin, C-natriuretic peptide (CNP) and nitric oxide (NO), may play a role in arterial blood gas-induced alterations in CBF. For the first time, we directly quantified exchang...

The case history is presented of a patient with acute respiratory failure complicated by nasal obstruction resulting in intolerance of nasal ventilation. Urgent insertion of nasal stents permitted restoration of ventilation with resolution of breathlessness and stabilisation of arterial blood gases. (Thorax 2000;55:434–436)

arterial blood gas (abg) sampling is a painful procedure with no perfect technique for quelling the discomfort. an ideal local anesthesia should be rapid, easy to learn, inexpensive, and noninvasive. this study was aimed to compare pain levels from abg sampling performed with vapocoolant spray in comparison to placebo. we hypothesized that pretreatment with the vapocoolant would reduce the pain...

BACKGROUND Point-of-care (POC) testing is highly useful when treating critically ill patients. In case of difficult vascular access, the intraosseous (IO) route is commonly used, and blood is aspirated to confirm the correct position of the IO-needle. Thus, IO blood samples could be easily accessed for POC analyses in emergency situations. The aim of this study was to determine whether IO value...

The case history is presented of a patient with acute respiratory failure complicated by nasal obstruction resulting in intolerance of nasal ventilation. Urgent insertion of nasal stents permitted restoration of ventilation with resolution of breathlessness and stabilisation of arterial blood gases.

Objectives: To describe the diurnal and nocturnal findings of 4 adults (3 women) and one child with systemic lupus erythematosus and shrinking lung syndrome. Design: A prospective observational study. Setting: A 750 teaching-bed-hospital with a reference population of 350,000 people. Interventions: Clinical history, blood analysis, imaging test, pulmonary function tests, maximal inspiratory and...

In underwater diving, decompression schedules are based on compartmental models of nitrogen and helium tissue kinetics. However, these models are not based on direct measurements of nitrogen and helium kinetics. In isoflurane-anesthetized sheep, nitrogen and helium kinetics in the hind limb (n = 5) and brain (n = 5) were determined during helium-oxygen breathing and after return to nitrogen-oxy...