BACKGROUND Experimental studies in vitro suggest that neutrophils can modulate platelet function and vasomotor responses. In the present study, the interactions among neutrophils, platelets, and arterial responses to injury in vivo were assessed. METHODS AND RESULTS The acute thrombotic and vasomotor responses of porcine carotid arteries to balloon injury in vivo were evaluated in three group...

Figure 1. Intravascular ultrasound images of 2 femoropopliteal lesions before (upper panels) and after (lower panels) treatment with the orbital atherectomy system (OAS). In A, there is a monolayer appearance (arrowheads in lower panel) of the arterial wall after OAS, indicating disappearing medial and intimal layers in the middle of a medial dissection (small arrows). In B, there is neither a ...

Selective operative management of injuries to the tibial arteries is controversial, with necessity revascularization in face multiple debated. Tibial artery are frequently encountered military trauma, but practices and outcomes poorly defined. We aimed investigate associations between number injured vessels reconstruction limb loss rates casualties arterial trauma. A US database lower extremity...

To systematically review the literature published on catheter-directed intra-arterial thrombolysis for management of severe frostbite injuries. Using three databases, a systematic was performed following Preferred Reporting Items Systematic Reviews and Meta-analyses (PRISMA) guidelines. Outcomes measured include procedure intervention protocol, number digits at risk, amputations performed, digi...

P-selectin expression has been reported in platelets, endothelial cells, and vascular smooth muscle cells in response to vascular injury. Here, we report P-selectin expression on macrophages in the arterial wall after carotid denudation injury and spontaneous atherosclerosis in atherosclerosis-prone apoE-deficient (apoE(-/-)) mice. Double-immunofluorescence staining revealed robust P-selectin e...

BACKGROUND It has been proposed that partial liquid ventilation (PLV) causes a compression of the pulmonary vasculature by the dense perfluorocarbons and a subsequent redistribution of pulmonary blood flow from dorsal to better-ventilated middle and ventral lung regions, thereby improving arterial oxygenation in situations of acute lung injury. METHODS After induction of acute lung injury by ...

Blunt traumatic injuries to the superior gluteal artery are rare in clinic. A majority of injuries present as aneurysms following penetrating trauma, fracture pelvis or posterior dislocation of the hip joint. We reported a rare case of superior gluteal artery pseudoaneurysm following blunt trauma presenting as large expanding right gluteal hematoma without any bony injury. The gluteal hematoma ...

The early response to coronary artery injury was investigated in normal swine and in swine with von Willebrand disease (vWD). Thirty minutes after coronary endothelial denudation, a monolayer of platelets was adherent to areas of simple injury in both bleeder and normal swine. The number of adherent platelets was not significantly different in the two phenotypes. Injury involving the media of t...

Pelvic ring fractures are common in the elderly population and are usually a result of low-energy trauma, such as falls from standing. In most cases, low-energy pelvic ring injuries can be treated with appropriate analgesia and early mobilization. Arterial injury resulting in hemodynamic instability from a low-energy pelvic ring injury is rare but, given the poor compliance of vessels in the el...