Aim: Oxidative stress is one of the causes contrast-induced nephropathy (CIN). Paraoxonase1 (PON1), oxidative markers. The most sensitive method that has been in use to measure PON1 enzyme activity measurement arylesterase (AREase) activity. To explore relationship between AREase and CIN development.
 Material Method: A total 58 STEMI patients were included our study. divided into two grou...

BACKGROUND Vanadyl sulfate (VS) and taurine are two promising agents in the treatment of diabetes related to their antihyperglycemic, antihyperlipidemic, and hyperinsulinemic effects. Data about the effects of VS on the oxidant-antioxidant system is limited and controversial. However, taurine is a well-documented antioxidant agent and our aim was to investigate the effects of VS, taurine and VS...

background: many studies have investigated the possible role of reactive oxygen species in the etiology and patho­gene­sis of rheumatoid arthritis (ra). the aim of this study was to investigate the activities of some antioxidants in ra patients. methods: in this case-control study, 59 ra patients and 60 healthy sex and age-matched controls were selected. vitamin e and beta-carotene were determi...

BACKGROUND Epidemiologic studies suggest that maternal organophosphorus (OP) pesticide exposure is associated with poorer fetal growth, but findings are inconsistent. We explored whether paraoxonase (PON1), a key enzyme involved in detoxification of OPs, could be an effect modifier in this association. METHODS The study population included 470 pregnant women enrolled in the CHAMACOS Study, a ...

Low-density lipoproteins (LDLs), when modified by free radicals derived from artery wall cells, induce atherosclerosis. In contrast to oxidized LDL (ox-LDL), high-density lipoproteins (HDLs) are able to prevent atherosclerosis through a protein with antioxidant properties, paraoxonase 1 (PON1). The purpose of this study was to explore the association between the activity of HDL-associated PON1 ...