نتایج جستجو برای: as2o3
تعداد نتایج: 328 فیلتر نتایج به سال:
The influence of hydrogen on the mechanical behavior a quenched and tempered 42CrMo4 steel has been evaluated by means high internal pressure fracture tests carried out precharged notched cylindrical specimens. specimens were in 1 M H2SO4 + 0.25 g/l As2O3 solution for 3 h with 1.2 mA/cm2. Hydraulic performed at different loading rates. Hydrogen embrittlement resistance increased grain size refi...
favorable outcome of APL with front-line RA plus chemotherapy, only few patients may be the subject of investigation for treatment of relapse.5-7 Finally, the effectiveness of As2O3 for consolidation of RA+chemotherapy induced remission as well as its potential synergism with retinoids front-line are being assessed in ongoing studies. Francesco Lo Coco Dept. of Human Biotechnology and Hematolog...
All-trans retinoic acid (tRA)-induced differentiation in NB4 cells, a cell line derived from an acute promyelocytic leukemia patient with t(15;17) translocation, is markedly facilitated by sodium butyrate (NaB), a histone deacetylase inhibitor (HDACI), or by hexamethylene bisacetamide (HMBA), a non-HDACI tRA-differentiation inducer, as determined by nitroblue tetrazolium reduction. The tRA-indu...
In this issue, Zou et al. report that vitamin C abrogated the ability of bortezomib (PS-341, Velcade) to induce apoptosis, G2-M arrest, and cleavage of caspase 8, caspase 3, and poly(ADP-ribose) polymerase and to augment tumor necrosis factor–related apoptosis-inducing ligand–induced apoptosis in various human cancer cell lines (1). Moreover, vitamin C suppressed bortezomib-mediated inhibition ...
Tetraarsenic hexoxide (As4O6) has been used in Korean traditional medicine for the treatment of cancer since the late 1980's, and arsenic trioxide (As2O3) is currently used as a chemotherapeutic agent. Previous studies suggest that the As4O6-induced cell death pathway is different from that of As2O3 and its mechanism of anticancer activity remains unclear. Nuclear factor (NF)-κB is a well-known...
The extent of and factors controlling arsenic penetration into the central nervous system (CNS) remain unclear. Elemental arsenic levels in 67 paired cerebrospinal fluid (CSF) and plasma samples from 9 patients with acute promyelocytic leukemia (APL) on oral arsenic trioxide (As2O3), obtained during intrathecal chemotherapy (treatment of CNS APL, n = 6; prophylaxis, n = 3) were measured. Median...
There is increasing evidence that L-ascorbic acid (LAA) is selectively toxic to some types of cancer cells at pharmacological concentrations, functioning as a pro-oxidant rather than as an anti-oxidant. However, the molecular mechanisms by which LAA initiates cellular signaling leading to cell death are still unclear. In an effort to gain insight into these mechanisms, the effects of LAA on euk...
Removing of arsenic and antimony from electrolyte copper electrorefining plant by cooling treatment is the subject current study. In this regards, temperature various samples reduce to 5, 10, 15 20 °C hold at different times without any turbulency. Experimental results reveal that decreasing electrolyte, facilitate deposition As Sb in form AsO5Sb, AsO4Sb As2O3 as white precipitate a critical ti...
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