Death from trauma is most often the result of uncontrollable bleeding as a result of Acute Traumatic Coagulopathy (ATC), a disease that manifests itself differently in different subcohorts of trauma patients. Understanding the mechanisms of ATC and how existing patient tests can inform us about these mechanisms is key to treating the disease. We introduce a hierarchical Canonical Correlation An...

Tutoring systems that engage each student as both a tutee and a tutor can be powerfully enhanced by motivating each tutor to try to appropriately challenge their tutee. The BEEweb platform is presented as a foundation upon which to build such systems, based upon the Reciprocal Tutoring protocol and the Teachers Dilemma. Three systems that have recently been built on the BEEweb platform are intr...

The need for determining and maintaining quality in the process of designing, developing and delivering online courses is becoming an important issue for universities and institutions worldwide. Teaching online may be a different process to conventional teaching, involving possible changes to pedagogy and teaching practice such as learner-centered education and collaborative learning. According...

Adaptive design is usually defined as the use of accumulating data obtained during the conduct of the trial to decide how to modify aspects of the trial as it progresses, without affecting its validity and integrity (Gallo et al., 2006). This form of research design involves a prospectively planned opportunity to modify the parameters of the study based on analysis of interim data while the stu...

In the absence of frictions if a portfolio strategy replicates the payoff of one unit of a claim, an appropriately scaled strategy replicates any amount of the claim. If assets are priced by arbitrage, the value per-unit is invariant to the amount of the asset considered. In particular, in the case of American claims, the optimal exercise time is independent of the amount of the claim that is c...

Tires are perhaps the most important, but difficult to model, component of an automobile. In addition to supporting the vehicle and damping out road irregularities, the tires provide the longitudinal and lateral forces necessary to change the speed and direction of the vehicle. These forces are produced by the deformation of the tire where it contacts the road during acceleration, braking, and ...

While it is well accepted that cooperative spectrum sensing will significantly improve the sensing performance, the necessity of cooperation is not sufficiently appreciated. In this paper, by analyzing the spectrum sensing problem from the system perspective, we show that without cooperation, the performance will suffer from a fundamental tradeoff between reliability and efficiency. However, if...