Advanced live-cell imaging of the endosomal sorting complexes required for transport (ESCRT) and computational modeling have provided insights into the Vps4-dependent dynamic rearrangements of ESCRT-III filaments during membrane constriction and abscission.

Building on earlier work on type inference directives for scripting a compiler to improve type error messages, we present extensions to those directives to deal with type classes. Our work is mainly motivated by the need for better type error messages, especially for domain specific languages. Type inference directives can bridge the gap between embedded domain specific languages and Haskell by...

vector spaces

The ”blazar phenomenon” is due to the presence of relativistic flows (jets) emanating from the nuclei of active galaxies which are radio loud. The power to energize the radio lobes is transported in the jets. Blazars are the subset of radio loud AGN for which the relativistic jet happens to point at small angles to the line of sight. Since the radiation emitted by the jet is relativistically be...

While the compensation for many nursing roles is published and accessible, no data have heretofore been available on monetary compensation for nurse editors. Answers to questions about compensation contained in a 108-question international survey of 88 editors of nursing journals, which was designed to learn about all aspects of the role of editor, are described. This study provides a first loo...

Abstract. For the first participation in the TREC Total Recall track, we set out to try some basic changes to the baseline provided by the organisers. Namely, the weighting scheme, the use of stopwords, and the number of learners that contribute to the decision of which documents to ask the virtual assessor to review. We observed that the baseline was extremely strong and none of the runs signi...

brings to the institute a strong academic standing , excellent administrative and leadership experience, and a far-reaching international network of scientists. I am sitting in the beautiful westward-facing dining room at the Banff Centre, watching the sun set gloriously into the Rocky Mountains. Even with it all in front of me, it is still hard to grasp the reality that the mathematicians of W...

In the 18th century, there was no standardized training for practitioners of medicine (or " physic(k), " as it was referred to at the time). The level of care sick individuals received was proportional to their social status, and diagnosis and treatment of illnesses varied widely between doctors. Medicine at Yale: The First 200 Years is the story of the evolution of medical training and practic...

One adult and one childhood case of concealed homicide by strangulation are presented. Both cases were first recognised on formal neck dissection at necropsy. Neither showed any obvious external trauma to the neck or laryngeal fracture. External petechiae were absent in the child. The pattern of internal injuries in both cases suggested that the likely mechanism was strangulation. Particular ca...

has no solutions which can be written using elementary functions, or anti-derivatives of elementary functions, or exponentials of such anti-derivatives, or anti-derivative of those, etc. We should note that Equation 1 can be solved using power series, integrals which depend on a parameter, or Bessel functions of order 1/3. However, as we will see, none of these methods of solution are “algebrai...