BACKGROUND The homeostasis model assessment of insulin resistance (HOMA-IR) is a useful model for application at large epidemiologic studies. The aim of this study was to determine the HOMA cut off values to identify insulin resistance (IR) and metabolic syndrome (MS) in Qazvin, central Iran. METHODS Overall, 480 men and 502 women aged 20-72 yr attended in this cross sectional study from Sept...

BACKGROUND Metabolic syndrome (MetS) is defined by the Third Report of the Adult Treatment Panel (ATP III) using criteria easily applied by clinicians and researchers. There is no standard pediatric definition. METHODS AND RESULTS We defined pediatric MetS using criteria analogous to ATP III as > or =3 of the following: (1) fasting triglycerides > or =1.1 mmol/L (100 mg/dL); (2) HDL <1.3 mmol...

Background: Beneficial effects of vitamins and dietary supplements in the prevention and treatment of metabolic syndrome (MS) are controversial. This study aims to evaluate the association between dietary supplements intake and MS. Methods: This analytical cross-sectional analysis was conducted on 9539 people aged 35-70 years who participated in the recruitment phase of Shahedieh Cohort Study i...

BACKGROUND AND OBJECTIVES Prevalence of metabolic syndrome is high among Asians including Indians. Scarce information is available about the magnitude of metabolic syndrome in rural areas and hence present study in rural area of Wardha district, central India. METHODS In 300 randomly selected subjects, blood pressure and anthropometric measurements such as height, weight, waist circumference ...

BACKGROUND Coronary Artery Disease (CAD) is a leading cause of death and disability in Kerala, India. Metabolic syndrome (MS) is a constellation of established risk factors for CAD. We aimed to estimate the prevalence of MS and evaluate the association between MS and CAD using a community-based sample population. METHODS A cross-sectional community based survey was conducted in urban and rura...

Methods: In this retrospective case control study we analyzed 149 subjects in total, 39 euthyroid and 110 hypothyroid subjects. Metabolic Syndrome was defined as per ATP III criteria. All data were collected through chart review. Study groups were analyzed for differences in baseline demographic variables including age, gender, smoking status and alcohol consumption. Statistical analyses perfor...

objective: previous studies have shown that up to 50% to 70% of patients with irritable bowel syndrome (ibs) who seek treatment have psychiatric comorbidity. the aim of this study was to report the history of anxiety and depression in ibs patients. methods: the study, designed as a cross-sectional, was performed in a consecutive sample of individuals diagnosed with ibs in the gastroenterology c...

BACKGROUND The presence of impaired glucose tolerance (IGT) and metabolic syndrome (MetS) are two risk factors for Type 2 diabetes. The inter-relatedness of these factors among adolescents is unclear. METHODS We evaluated the sensitivity and specificity of MetS for identifying IGT in an unselected group of adolescents undergoing oral glucose tolerance tests (OGTT) in the National Health and N...

BACKGROUND The metabolic syndrome consists of a cluster of atherosclerotic risk factors, many of which also have been implicated in the genesis of atrial fibrillation (AF). However, the precise role of the metabolic syndrome in the development of AF is unknown. METHODS AND RESULTS This prospective, community-based, observational cohort study was based on an annual health check-up program in J...

We have covalently modified the recA protein from Escherichia coli with the photoaffinity ATP analog 8-azido-[alpha-32P]ATP (N3-ATP). Covalent attachment of N3-ATP to recA protein is dependent on native protein conformation and is shown to be specific for the site of ATP hydrolysis by the following criteria. (i) Binding of the probe to recA protein is inhibited by ATP and competitive inhibitors...